Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
plu1872N-acetyltransferase domain-containing protein; Unnamed protein product; Similar to hypothetical acetyltransferase. (153 aa)    
Predicted Functional Partners:
plu1870
Aconitase_C domain-containing protein; Unnamed protein product; Similar to 3-isopropylmalate dehydratase, small subunit (leuD-2); Belongs to the LeuD family.
      
 0.623
plu1871
Methyltransf_25 domain-containing protein; Unnamed protein product; Some similarities with putative methyltransferases.
      
 0.623
mrcA
Penicillin-binding protein 1A (PBP-1a) (PBP1a) (penicillin-binding protein A) [Includes: Penicillin-insensitive transglycosylase (Peptidoglycan TGase); Penicillin-sensitive transpeptidase (DD-transpeptidase)].
      
 0.540
typA
GTPase.
      
 0.540
php
Phosphotriesterase homology protein.
      
 0.540
xseA
Exodeoxyribonuclease VII large subunit (exonuclease VII large subunit); Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.
      
 0.540
treC
Trehalose-6-phosphate hydrolase (alpha,alpha-phosphotrehalase).
      
 0.540
cpxP
Periplasmic protein precursor.
      
 0.540
trmE
tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
      
 0.539
gltB
Glutamate synthase [NADPH] large chain precursor (glutamate synthase alpha subunit) (NADPH-GOGAT) (GLTS alpha chain).
     
 0.421
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.