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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
plu1884Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; Unnamed protein product; Some similarities with dihydrolipoamide acyltransferase and succinyltransferase. (521 aa)    
Predicted Functional Partners:
plu1883
Transket_pyr domain-containing protein; Unnamed protein product; Similar to 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) alpha/beta E1 chain CP0743.
 
 0.999
plu2795
Transket_pyr domain-containing protein; Unnamed protein product; Similar to 3-methyl-2-oxobutanoate dehydrogenase (lipoamide). Putative transmembrane protein.
 
 0.998
sucA
2-oxoglutarate dehydrogenase E1 component (Alpha-ketoglutarate dehydrogenase).
 
 0.994
lpdA
Dihydrolipoamide dehydrogenase (E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes) (glycine cleavage system L protein).
 
 0.990
sucC
succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 0.969
sucD
succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 0.963
sucB
Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex (E2); E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
  
  
 
0.929
gor
Glutathione oxidoreductase (GR) (GRase).
 
 0.825
sthA
Soluble pyridine nucleotide transhydrogenase (STH) (NAD(P)(+) transhydrogenase [B-specific]); Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
 
 0.813
plu0146
Unnamed protein product; Similar to beta-ketoadipyl CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.811
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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