STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fliZFliZ protein. (170 aa)    
Predicted Functional Partners:
fliA
RNA polymerase sigma factor for flagellar operon (Sigma-F factor) (Sigma-27) (Sigma-28); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily.
  
  
 0.947
flgK
Flagellar hook-associated protein 1 (HAP1).
   
   0.813
fliT
Flagellar protein FliT; Dual-function protein that regulates the transcription of class 2 flagellar operons and that also acts as an export chaperone for the filament-capping protein FliD. As a transcriptional regulator, acts as an anti-FlhDC factor; it directly binds FlhC, thus inhibiting the binding of the FlhC/FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus.
  
  
 0.755
flgB
Flagellar basal-body rod protein FlgB (Putative proximal rod protein); Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
   
  
 0.746
fliC
Flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
  
  
 0.743
fliD
Flagellar hook-associated protein 2 (HAP2) (Filament cap protein) (Flagellar cap protein); Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
  
  
 0.741
flgM
Negative regulator of flagellin synthesis (Anti-sigma-28 factor) FlgM.
   
  
 0.701
fliS
Flagellar protein FliS.
  
    0.690
flgN
Flagella synthesis protein FlgN.
   
  
 0.674
flgD
Basal-body rod modification protein FlgD (flagellar protein for the initiation of hook assembly); Required for flagellar hook formation. May act as a scaffolding protein.
   
    0.668
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.