| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| fruA | fruB | plu1993 | plu1992 | PTS system, fructose-specific IIBC component. | PTS system, fructose-specific IIA/FPr component. | 0.999 |
| fruA | fruK | plu1993 | plu2858 | PTS system, fructose-specific IIBC component. | 1-phosphofructokinase (fructose 1-phosphate kinase); Belongs to the carbohydrate kinase PfkB family. | 0.999 |
| fruA | manX | plu1993 | plu2697 | PTS system, fructose-specific IIBC component. | PTS system, mannose-specific IIAB component (EIIAB-MAN) (Mannose-permease IIAB component) (Phosphotransferase enzyme II, AB component) (EIII-MAN). | 0.685 |
| fruA | nagE | plu1993 | plu1318 | PTS system, fructose-specific IIBC component. | PTS system, N-acetylglucosamine-specific IIABC component (EIIABC-NAG) (N-acetylglucosamine-permease IIABC component) (Phosphotransferase enzyme II, ABC component) (EII-NAG). | 0.804 |
| fruA | plu0585 | plu1993 | plu0585 | PTS system, fructose-specific IIBC component. | Unnamed protein product; Similar to beta-glucoside permease IIABC component (phosphotransferase enzyme II, ABC component). Putative transmembrane protein. | 0.898 |
| fruA | ptsH | plu1993 | plu1394 | PTS system, fructose-specific IIBC component. | Phosphocarrier protein HPr (Histidine-containing protein). | 0.990 |
| fruA | ptsI | plu1993 | plu1393 | PTS system, fructose-specific IIBC component. | Phosphoenolpyruvate-protein phosphotransferase (Phosphotransferase system, enzyme I); General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). | 0.933 |
| fruA | ptsN | plu1993 | plu4043 | PTS system, fructose-specific IIBC component. | Nitrogen regulatory IIA protein (enzyme IIA-NTR) (phosphotransferase enzyme II, A component). | 0.916 |
| fruA | ptsP | plu1993 | plu0621 | PTS system, fructose-specific IIBC component. | Phosphoenolpyruvate-protein phosphotransferase PtsP (Phosphotransferase system, enzyme I) (Enzyme I-Ntr); Belongs to the PEP-utilizing enzyme family. | 0.678 |
| fruA | uxuB | plu1993 | plu0175 | PTS system, fructose-specific IIBC component. | D-mannonate oxidoreductase (fructuronate reductase); Belongs to the mannitol dehydrogenase family. | 0.574 |
| fruB | fruA | plu1992 | plu1993 | PTS system, fructose-specific IIA/FPr component. | PTS system, fructose-specific IIBC component. | 0.999 |
| fruB | fruK | plu1992 | plu2858 | PTS system, fructose-specific IIA/FPr component. | 1-phosphofructokinase (fructose 1-phosphate kinase); Belongs to the carbohydrate kinase PfkB family. | 0.986 |
| fruB | manX | plu1992 | plu2697 | PTS system, fructose-specific IIA/FPr component. | PTS system, mannose-specific IIAB component (EIIAB-MAN) (Mannose-permease IIAB component) (Phosphotransferase enzyme II, AB component) (EIII-MAN). | 0.889 |
| fruB | nagE | plu1992 | plu1318 | PTS system, fructose-specific IIA/FPr component. | PTS system, N-acetylglucosamine-specific IIABC component (EIIABC-NAG) (N-acetylglucosamine-permease IIABC component) (Phosphotransferase enzyme II, ABC component) (EII-NAG). | 0.759 |
| fruB | plu0585 | plu1992 | plu0585 | PTS system, fructose-specific IIA/FPr component. | Unnamed protein product; Similar to beta-glucoside permease IIABC component (phosphotransferase enzyme II, ABC component). Putative transmembrane protein. | 0.823 |
| fruB | ptsH | plu1992 | plu1394 | PTS system, fructose-specific IIA/FPr component. | Phosphocarrier protein HPr (Histidine-containing protein). | 0.934 |
| fruB | ptsI | plu1992 | plu1393 | PTS system, fructose-specific IIA/FPr component. | Phosphoenolpyruvate-protein phosphotransferase (Phosphotransferase system, enzyme I); General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). | 0.999 |
| fruB | ptsN | plu1992 | plu4043 | PTS system, fructose-specific IIA/FPr component. | Nitrogen regulatory IIA protein (enzyme IIA-NTR) (phosphotransferase enzyme II, A component). | 0.788 |
| fruB | ptsP | plu1992 | plu0621 | PTS system, fructose-specific IIA/FPr component. | Phosphoenolpyruvate-protein phosphotransferase PtsP (Phosphotransferase system, enzyme I) (Enzyme I-Ntr); Belongs to the PEP-utilizing enzyme family. | 0.961 |
| fruB | uxuB | plu1992 | plu0175 | PTS system, fructose-specific IIA/FPr component. | D-mannonate oxidoreductase (fructuronate reductase); Belongs to the mannitol dehydrogenase family. | 0.926 |