Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
plu2037Unnamed protein product; Some high similarities with DNA-specific endonuclease I. Putative secreted protein. (332 aa)    
Predicted Functional Partners:
plu0547
SMI1_KNR4 domain-containing protein; Unnamed protein product; Similar to unknown protein.
  
     0.492
plu1139
Unnamed protein product; Similar to unknown protein.
  
     0.492
plu1148
Unnamed protein product; Similar to unknown protein.
  
     0.492
plu0421
Unnamed protein product; Highly similar to unknown protein. Putative secreted protein.
  
     0.481
plu2038
Unnamed protein product; Hypothetical gene.
       0.475
thiI
tRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
  
   
 0.449
plu2036
Unnamed protein product; Some similarities with unknown protein from prophage CP-933H.
       0.434
cpxP
Periplasmic protein precursor.
  
     0.426
sprT
Protein sprT; Belongs to the SprT family.
     
 0.424
mutL
DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
      
 0.405
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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