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Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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luxDAcyl transferase; Acyl transferase is part of the fatty acid reductase system required for aldehyde biosynthesis; it produces fatty acids for the luminescent reaction; Belongs to the LuxD family. (307 aa)    
Predicted Functional Partners:
luxC
Fatty acid reductase; LuxC is the fatty acid reductase enzyme responsible for synthesis of the aldehyde substrate for the luminescent reaction catalyzed by luciferase.
     
 0.914
plu2321
Unnamed protein product; Similar to protein HMWP1 of Yersinia enterocolitica.
  
 0.808
plu1880
Unnamed protein product; Similar to proteins involved in antibiotic biosynthesis. Putative transmembrane protein.
  
 0.759
luxE
Acyl-protein synthetase (long-chain-fatty-acid-luciferin-component ligase).
  
  
 0.724
birA
Bifunctional protein [Includes: biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
     
 0.670
luxA
Alkanal monooxygenase alpha chain (Bacterial luciferase alpha chain); Light-emitting reaction in luminous bacteria.
  
  
 0.618
luxB
Alkanal monooxygenase beta chain (luciferase beta subunit); Light-emitting reaction in luminous bacteria. The specific role of the beta subunit is unknown, but it is absolutely required for bioluminescence activity.
  
  
 0.618
plu1878
Carrier domain-containing protein; Unnamed protein product; Similar to antibiotic synthetase.
   
 
 0.470
trpC
Tryptophan biosynthesis protein TrpCF [includes: indole-3-glycerol phosphate synthase (IGPS); N-(5'-phospho-ribosyl)anthrnilate isomerase (PRAI)].
   
 
 0.465
plu2642
Carrier domain-containing protein; Unnamed protein product; Similar to proteins involved in antibiotic biosynthesis. Putative transmembrane protein.
   
 
 0.439
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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