| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| birA | luxD | plu4732 | plu2080 | Bifunctional protein [Includes: biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Acyl transferase; Acyl transferase is part of the fatty acid reductase system required for aldehyde biosynthesis; it produces fatty acids for the luminescent reaction; Belongs to the LuxD family. | 0.478 |
| birA | plu1880 | plu4732 | plu1880 | Bifunctional protein [Includes: biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Unnamed protein product; Similar to proteins involved in antibiotic biosynthesis. Putative transmembrane protein. | 0.515 |
| birA | plu2321 | plu4732 | plu2321 | Bifunctional protein [Includes: biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Unnamed protein product; Similar to protein HMWP1 of Yersinia enterocolitica. | 0.546 |
| luxA | luxB | plu2081 | plu2082 | Alkanal monooxygenase alpha chain (Bacterial luciferase alpha chain); Light-emitting reaction in luminous bacteria. | Alkanal monooxygenase beta chain (luciferase beta subunit); Light-emitting reaction in luminous bacteria. The specific role of the beta subunit is unknown, but it is absolutely required for bioluminescence activity. | 0.983 |
| luxA | luxC | plu2081 | plu2079 | Alkanal monooxygenase alpha chain (Bacterial luciferase alpha chain); Light-emitting reaction in luminous bacteria. | Fatty acid reductase; LuxC is the fatty acid reductase enzyme responsible for synthesis of the aldehyde substrate for the luminescent reaction catalyzed by luciferase. | 0.541 |
| luxA | luxD | plu2081 | plu2080 | Alkanal monooxygenase alpha chain (Bacterial luciferase alpha chain); Light-emitting reaction in luminous bacteria. | Acyl transferase; Acyl transferase is part of the fatty acid reductase system required for aldehyde biosynthesis; it produces fatty acids for the luminescent reaction; Belongs to the LuxD family. | 0.680 |
| luxA | luxE | plu2081 | plu2083 | Alkanal monooxygenase alpha chain (Bacterial luciferase alpha chain); Light-emitting reaction in luminous bacteria. | Acyl-protein synthetase (long-chain-fatty-acid-luciferin-component ligase). | 0.661 |
| luxA | plu1878 | plu2081 | plu1878 | Alkanal monooxygenase alpha chain (Bacterial luciferase alpha chain); Light-emitting reaction in luminous bacteria. | Carrier domain-containing protein; Unnamed protein product; Similar to antibiotic synthetase. | 0.450 |
| luxA | plu1880 | plu2081 | plu1880 | Alkanal monooxygenase alpha chain (Bacterial luciferase alpha chain); Light-emitting reaction in luminous bacteria. | Unnamed protein product; Similar to proteins involved in antibiotic biosynthesis. Putative transmembrane protein. | 0.523 |
| luxA | plu2321 | plu2081 | plu2321 | Alkanal monooxygenase alpha chain (Bacterial luciferase alpha chain); Light-emitting reaction in luminous bacteria. | Unnamed protein product; Similar to protein HMWP1 of Yersinia enterocolitica. | 0.557 |
| luxA | plu2642 | plu2081 | plu2642 | Alkanal monooxygenase alpha chain (Bacterial luciferase alpha chain); Light-emitting reaction in luminous bacteria. | Carrier domain-containing protein; Unnamed protein product; Similar to proteins involved in antibiotic biosynthesis. Putative transmembrane protein. | 0.418 |
| luxB | luxA | plu2082 | plu2081 | Alkanal monooxygenase beta chain (luciferase beta subunit); Light-emitting reaction in luminous bacteria. The specific role of the beta subunit is unknown, but it is absolutely required for bioluminescence activity. | Alkanal monooxygenase alpha chain (Bacterial luciferase alpha chain); Light-emitting reaction in luminous bacteria. | 0.983 |
| luxB | luxC | plu2082 | plu2079 | Alkanal monooxygenase beta chain (luciferase beta subunit); Light-emitting reaction in luminous bacteria. The specific role of the beta subunit is unknown, but it is absolutely required for bioluminescence activity. | Fatty acid reductase; LuxC is the fatty acid reductase enzyme responsible for synthesis of the aldehyde substrate for the luminescent reaction catalyzed by luciferase. | 0.541 |
| luxB | luxD | plu2082 | plu2080 | Alkanal monooxygenase beta chain (luciferase beta subunit); Light-emitting reaction in luminous bacteria. The specific role of the beta subunit is unknown, but it is absolutely required for bioluminescence activity. | Acyl transferase; Acyl transferase is part of the fatty acid reductase system required for aldehyde biosynthesis; it produces fatty acids for the luminescent reaction; Belongs to the LuxD family. | 0.680 |
| luxB | luxE | plu2082 | plu2083 | Alkanal monooxygenase beta chain (luciferase beta subunit); Light-emitting reaction in luminous bacteria. The specific role of the beta subunit is unknown, but it is absolutely required for bioluminescence activity. | Acyl-protein synthetase (long-chain-fatty-acid-luciferin-component ligase). | 0.665 |
| luxB | plu1878 | plu2082 | plu1878 | Alkanal monooxygenase beta chain (luciferase beta subunit); Light-emitting reaction in luminous bacteria. The specific role of the beta subunit is unknown, but it is absolutely required for bioluminescence activity. | Carrier domain-containing protein; Unnamed protein product; Similar to antibiotic synthetase. | 0.450 |
| luxB | plu1880 | plu2082 | plu1880 | Alkanal monooxygenase beta chain (luciferase beta subunit); Light-emitting reaction in luminous bacteria. The specific role of the beta subunit is unknown, but it is absolutely required for bioluminescence activity. | Unnamed protein product; Similar to proteins involved in antibiotic biosynthesis. Putative transmembrane protein. | 0.523 |
| luxB | plu2321 | plu2082 | plu2321 | Alkanal monooxygenase beta chain (luciferase beta subunit); Light-emitting reaction in luminous bacteria. The specific role of the beta subunit is unknown, but it is absolutely required for bioluminescence activity. | Unnamed protein product; Similar to protein HMWP1 of Yersinia enterocolitica. | 0.557 |
| luxB | plu2642 | plu2082 | plu2642 | Alkanal monooxygenase beta chain (luciferase beta subunit); Light-emitting reaction in luminous bacteria. The specific role of the beta subunit is unknown, but it is absolutely required for bioluminescence activity. | Carrier domain-containing protein; Unnamed protein product; Similar to proteins involved in antibiotic biosynthesis. Putative transmembrane protein. | 0.418 |
| luxC | luxA | plu2079 | plu2081 | Fatty acid reductase; LuxC is the fatty acid reductase enzyme responsible for synthesis of the aldehyde substrate for the luminescent reaction catalyzed by luciferase. | Alkanal monooxygenase alpha chain (Bacterial luciferase alpha chain); Light-emitting reaction in luminous bacteria. | 0.541 |