Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nudBdATP pyrophosphohydrolase. (145 aa)    
Predicted Functional Partners:
aspS
aspartyl-tRNA synthetase (aspartate--tRNA ligase) (asprs); Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
  
   0.929
plu2109
Probable transcriptional regulatory protein plu2109; Unnamed protein product; Highly similar to unknown protein YebC of Escherichia coli.
  
    0.929
folE
GTP cyclohydrolase I (GTP-CH-I).
  
 
  0.907
plu2793
GTP_cyclohydroI domain-containing protein; Unnamed protein product; Some similarities with GTP cyclohydrolase I precursor.
  
 
  0.907
phoA
Alkaline phosphatase precursor (APASE); Belongs to the alkaline phosphatase family.
     
 0.902
plu0702
6-carboxy-5,6,7,8-tetrahydropterin synthase; Unnamed protein product; Highly similar to putative 6-pyruvoyl tetrahydrobiopterin synthase (PTPS).
    
  0.901
plu2794
Unnamed protein product; Some similarities with 6-pyruvoyl tetrahydrobiopterin synthase.
    
  0.901
ruvC
Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
  
  
 0.619
plu4310
Unnamed protein product; Some similarities with unknown protein.
  
     0.606
birA
Bifunctional protein [Includes: biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
   
    0.573
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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