| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| birA | mesJ | plu4732 | plu0689 | Bifunctional protein [Includes: biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Putative cell cycle protein MesJ; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.568 |
| birA | plu2132 | plu4732 | plu2132 | Bifunctional protein [Includes: biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Peptidase_M22 domain-containing protein; Unnamed protein product; Highly similar to hypothetical protease YeaZ of Escherichia coli. | 0.912 |
| birA | tadA | plu4732 | plu3320 | Bifunctional protein [Includes: biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.921 |
| gcp | plu2132 | plu3976 | plu2132 | O-sialoglycoprotein endopeptidase (glycoprotease); Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | Peptidase_M22 domain-containing protein; Unnamed protein product; Highly similar to hypothetical protease YeaZ of Escherichia coli. | 0.936 |
| gcp | plu4585 | plu3976 | plu4585 | O-sialoglycoprotein endopeptidase (glycoprotease); Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | Unnamed protein product; Similar to unknown protein YjeE of Escherichia coli. | 0.855 |
| hisI | plu2132 | plu1564 | plu2132 | phosphoribosyl-AMP cyclohydrolase (PRA-CH) / phosphoribosyl-ATP pyrophosphatase (PRA-PH); In the C-terminal section; belongs to the PRA-PH family. | Peptidase_M22 domain-containing protein; Unnamed protein product; Highly similar to hypothetical protease YeaZ of Escherichia coli. | 0.478 |
| hisI | tadA | plu1564 | plu3320 | phosphoribosyl-AMP cyclohydrolase (PRA-CH) / phosphoribosyl-ATP pyrophosphatase (PRA-PH); In the C-terminal section; belongs to the PRA-PH family. | tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.917 |
| mesJ | birA | plu0689 | plu4732 | Putative cell cycle protein MesJ; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | Bifunctional protein [Includes: biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.568 |
| mesJ | plu2132 | plu0689 | plu2132 | Putative cell cycle protein MesJ; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | Peptidase_M22 domain-containing protein; Unnamed protein product; Highly similar to hypothetical protease YeaZ of Escherichia coli. | 0.560 |
| mesJ | tadA | plu0689 | plu3320 | Putative cell cycle protein MesJ; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.461 |
| mesJ | truA | plu0689 | plu3173 | Putative cell cycle protein MesJ; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.621 |
| plu2132 | birA | plu2132 | plu4732 | Peptidase_M22 domain-containing protein; Unnamed protein product; Highly similar to hypothetical protease YeaZ of Escherichia coli. | Bifunctional protein [Includes: biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.912 |
| plu2132 | gcp | plu2132 | plu3976 | Peptidase_M22 domain-containing protein; Unnamed protein product; Highly similar to hypothetical protease YeaZ of Escherichia coli. | O-sialoglycoprotein endopeptidase (glycoprotease); Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.936 |
| plu2132 | hisI | plu2132 | plu1564 | Peptidase_M22 domain-containing protein; Unnamed protein product; Highly similar to hypothetical protease YeaZ of Escherichia coli. | phosphoribosyl-AMP cyclohydrolase (PRA-CH) / phosphoribosyl-ATP pyrophosphatase (PRA-PH); In the C-terminal section; belongs to the PRA-PH family. | 0.478 |
| plu2132 | mesJ | plu2132 | plu0689 | Peptidase_M22 domain-containing protein; Unnamed protein product; Highly similar to hypothetical protease YeaZ of Escherichia coli. | Putative cell cycle protein MesJ; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.560 |
| plu2132 | plu2133 | plu2132 | plu2133 | Peptidase_M22 domain-containing protein; Unnamed protein product; Highly similar to hypothetical protease YeaZ of Escherichia coli. | Unnamed protein product; Similar to hypothetical lipoprotein YeaY precursor of Escherichia coli. | 0.639 |
| plu2132 | plu3604 | plu2132 | plu3604 | Peptidase_M22 domain-containing protein; Unnamed protein product; Highly similar to hypothetical protease YeaZ of Escherichia coli. | 5-formyltetrahydrofolate cyclo-ligase; Unnamed protein product; Similar to putative ligase YgfA of Escherichia coli; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | 0.515 |
| plu2132 | plu4585 | plu2132 | plu4585 | Peptidase_M22 domain-containing protein; Unnamed protein product; Highly similar to hypothetical protease YeaZ of Escherichia coli. | Unnamed protein product; Similar to unknown protein YjeE of Escherichia coli. | 0.951 |
| plu2132 | recR | plu2132 | plu3839 | Peptidase_M22 domain-containing protein; Unnamed protein product; Highly similar to hypothetical protease YeaZ of Escherichia coli. | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.490 |
| plu2132 | tadA | plu2132 | plu3320 | Peptidase_M22 domain-containing protein; Unnamed protein product; Highly similar to hypothetical protease YeaZ of Escherichia coli. | tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.575 |
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