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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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Score
plu2198ATP-grasp domain-containing protein; Unnamed protein product; Similar to the phosphoribosylamine--glycine ligase. (420 aa)    
Predicted Functional Partners:
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
 
 0.999
purE
Phosphoribosylaminoimidazole carboxylase catalytic subunit (AIR carboxylase) (AIRC); Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
 
 0.999
purM
Phosphoribosylformylglycinamidine cyclo-ligase (AIRS) (phosphoribosyl-aminoimidazole synthetase) (AIR synthase).
  
 0.996
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
 
 0.994
purL
Phosphoribosylformylglycineamide synthetase (formylglycineamide ribonucleotide synthetase); Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
 
  
 0.992
purC
Phosphoribosylaminoimidazole-succinocarboxamide synthase (5'-phosphoribosyl-5-aminoimidazole-4-N-succinocarboxamide synthase); Belongs to the SAICAR synthetase family.
 
 
 0.988
purH
Phosphoribosylaminoimidazolecarboxamide formyltransferase and IMP cyclohydrolase (bifunctional enzyme).
 
 
 0.973
purB
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
 
 0.969
purK
Phosphoribosylaminoimidazole carboxylase ATPase subunit (AIR carboxylase) (AIRC); Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
 
  
 0.914
purD
Phosphoribosylglycinamide synthetase; Belongs to the GARS family.
  
  
 
0.910
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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