| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| gcvP | plu2198 | plu3596 | plu2198 | Glycine dehydrogenase [decarboxylating] (glycine decarboxylase) (glycine cleavage system P-protein); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | ATP-grasp domain-containing protein; Unnamed protein product; Similar to the phosphoribosylamine--glycine ligase. | 0.930 |
| gcvP | purC | plu3596 | plu2744 | Glycine dehydrogenase [decarboxylating] (glycine decarboxylase) (glycine cleavage system P-protein); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Phosphoribosylaminoimidazole-succinocarboxamide synthase (5'-phosphoribosyl-5-aminoimidazole-4-N-succinocarboxamide synthase); Belongs to the SAICAR synthetase family. | 0.742 |
| gcvP | purD | plu3596 | plu0494 | Glycine dehydrogenase [decarboxylating] (glycine decarboxylase) (glycine cleavage system P-protein); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Phosphoribosylglycinamide synthetase; Belongs to the GARS family. | 0.930 |
| gcvP | purE | plu3596 | plu3807 | Glycine dehydrogenase [decarboxylating] (glycine decarboxylase) (glycine cleavage system P-protein); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Phosphoribosylaminoimidazole carboxylase catalytic subunit (AIR carboxylase) (AIRC); Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.580 |
| gcvP | purF | plu3596 | plu3167 | Glycine dehydrogenase [decarboxylating] (glycine decarboxylase) (glycine cleavage system P-protein); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.785 |
| gcvP | purH | plu3596 | plu0495 | Glycine dehydrogenase [decarboxylating] (glycine decarboxylase) (glycine cleavage system P-protein); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Phosphoribosylaminoimidazolecarboxamide formyltransferase and IMP cyclohydrolase (bifunctional enzyme). | 0.770 |
| gcvP | purL | plu3596 | plu3317 | Glycine dehydrogenase [decarboxylating] (glycine decarboxylase) (glycine cleavage system P-protein); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Phosphoribosylformylglycineamide synthetase (formylglycineamide ribonucleotide synthetase); Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.929 |
| plu2198 | gcvP | plu2198 | plu3596 | ATP-grasp domain-containing protein; Unnamed protein product; Similar to the phosphoribosylamine--glycine ligase. | Glycine dehydrogenase [decarboxylating] (glycine decarboxylase) (glycine cleavage system P-protein); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.930 |
| plu2198 | purC | plu2198 | plu2744 | ATP-grasp domain-containing protein; Unnamed protein product; Similar to the phosphoribosylamine--glycine ligase. | Phosphoribosylaminoimidazole-succinocarboxamide synthase (5'-phosphoribosyl-5-aminoimidazole-4-N-succinocarboxamide synthase); Belongs to the SAICAR synthetase family. | 0.920 |
| plu2198 | purD | plu2198 | plu0494 | ATP-grasp domain-containing protein; Unnamed protein product; Similar to the phosphoribosylamine--glycine ligase. | Phosphoribosylglycinamide synthetase; Belongs to the GARS family. | 0.910 |
| plu2198 | purE | plu2198 | plu3807 | ATP-grasp domain-containing protein; Unnamed protein product; Similar to the phosphoribosylamine--glycine ligase. | Phosphoribosylaminoimidazole carboxylase catalytic subunit (AIR carboxylase) (AIRC); Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.993 |
| plu2198 | purF | plu2198 | plu3167 | ATP-grasp domain-containing protein; Unnamed protein product; Similar to the phosphoribosylamine--glycine ligase. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.994 |
| plu2198 | purH | plu2198 | plu0495 | ATP-grasp domain-containing protein; Unnamed protein product; Similar to the phosphoribosylamine--glycine ligase. | Phosphoribosylaminoimidazolecarboxamide formyltransferase and IMP cyclohydrolase (bifunctional enzyme). | 0.945 |
| plu2198 | purK | plu2198 | plu3808 | ATP-grasp domain-containing protein; Unnamed protein product; Similar to the phosphoribosylamine--glycine ligase. | Phosphoribosylaminoimidazole carboxylase ATPase subunit (AIR carboxylase) (AIRC); Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.894 |
| plu2198 | purL | plu2198 | plu3317 | ATP-grasp domain-containing protein; Unnamed protein product; Similar to the phosphoribosylamine--glycine ligase. | Phosphoribosylformylglycineamide synthetase (formylglycineamide ribonucleotide synthetase); Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.983 |
| plu2198 | purM | plu2198 | plu2760 | ATP-grasp domain-containing protein; Unnamed protein product; Similar to the phosphoribosylamine--glycine ligase. | Phosphoribosylformylglycinamidine cyclo-ligase (AIRS) (phosphoribosyl-aminoimidazole synthetase) (AIR synthase). | 0.994 |
| plu2198 | purN | plu2198 | plu2761 | ATP-grasp domain-containing protein; Unnamed protein product; Similar to the phosphoribosylamine--glycine ligase. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.999 |
| purC | gcvP | plu2744 | plu3596 | Phosphoribosylaminoimidazole-succinocarboxamide synthase (5'-phosphoribosyl-5-aminoimidazole-4-N-succinocarboxamide synthase); Belongs to the SAICAR synthetase family. | Glycine dehydrogenase [decarboxylating] (glycine decarboxylase) (glycine cleavage system P-protein); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.742 |
| purC | plu2198 | plu2744 | plu2198 | Phosphoribosylaminoimidazole-succinocarboxamide synthase (5'-phosphoribosyl-5-aminoimidazole-4-N-succinocarboxamide synthase); Belongs to the SAICAR synthetase family. | ATP-grasp domain-containing protein; Unnamed protein product; Similar to the phosphoribosylamine--glycine ligase. | 0.920 |
| purC | purD | plu2744 | plu0494 | Phosphoribosylaminoimidazole-succinocarboxamide synthase (5'-phosphoribosyl-5-aminoimidazole-4-N-succinocarboxamide synthase); Belongs to the SAICAR synthetase family. | Phosphoribosylglycinamide synthetase; Belongs to the GARS family. | 0.918 |
STRING v12.5 is now available!
