STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
plu2201FAA_hydrolase domain-containing protein; Unnamed protein product; Similar to 2-oxopent-4-dienoate hydratase. (260 aa)    
Predicted Functional Partners:
hpaI
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; Belongs to the HpcH/HpaI aldolase family.
  
 0.893
plu2202
AB hydrolase-1 domain-containing protein; Unnamed protein product; Similar to the 2-hydroxy-6-ketonona-2,4-dienedoic acid hydrolase.
 
  
 0.893
hpcD
5-carboxymethyl-2-hydroxy-muconic acid isomerase.
 
  
 0.884
hpcB
3,4-dihydroxyphenylacetate 2,3-dioxygenase.
 
  
 0.855
hcaE
3-phenylpropionate dioxygenase alpha subunit (digoxigenin alpha subunit); Part of the multicomponent 3-phenylpropionate dioxygenase. Converts 3-phenylpropionic acid (PP) and cinnamic acid (CI) into 3- phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid- dihydrodiol (CI-dihydrodiol), respectively.
 
   
 0.794
mhpB
2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase; Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3-dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2-hydroxy-6- ketononatrienedioate, respectively; Belongs to the LigB/MhpB extradiol dioxygenase family.
 
  
 0.772
hcaF
3-phenylpropionate dioxygenase beta subunit (digoxigenin beta subunit); Part of the multicomponent 3-phenylpropionate dioxygenase. Converts 3-phenylpropionic acid (PP) and cinnamic acid (CI) into 3- phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid- dihydrodiol (CI-dihydrodiol), respectively.
 
   
 0.716
plu1000
Rieske domain-containing protein; Unnamed protein product; Similar to salicylate-5-hydroxylase large oxygenase component.
 
   
 0.641
hpcR
Homoprotocatechuate degradation operon regulator.
 
     0.527
hpaA
Regulator of the 4HPA-hydroxylase operon.
 
    0.445
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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