Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hcaRHca operon transcriptional activator; Belongs to the LysR transcriptional regulatory family. (294 aa)    
Predicted Functional Partners:
lrhA
LrhA (HexA) may be a general repressor of primary-specific phenotype. lrhA expression is increased (at least 10-fold) in the secondary variant of K122, UK210 and TT01; Belongs to the LysR transcriptional regulatory family.
  
   
 0.759
plu2855
HTH lysR-type domain-containing protein; Unnamed protein product; Highly similar to putative transcriptional regulator LysR-type YeiE of Escherichia coli; Belongs to the LysR transcriptional regulatory family.
  
     0.757
plu2641
HTH lysR-type domain-containing protein; Unnamed protein product; Similar to transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.
  
     0.744
plu4133
HTH lysR-type domain-containing protein; Unnamed protein product; Similar to transcription regulator, LysR family; Belongs to the LysR transcriptional regulatory family.
  
     0.734
dsdC
D-serine dehydratase (deaminase) transcriptional activator DsdC; Belongs to the LysR transcriptional regulatory family.
  
     0.620
hcaE
3-phenylpropionate dioxygenase alpha subunit (digoxigenin alpha subunit); Part of the multicomponent 3-phenylpropionate dioxygenase. Converts 3-phenylpropionic acid (PP) and cinnamic acid (CI) into 3- phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid- dihydrodiol (CI-dihydrodiol), respectively.
 
     0.594
plu4260
HTH lysR-type domain-containing protein; Unnamed protein product; Similar to transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.
  
     0.588
plu2202
AB hydrolase-1 domain-containing protein; Unnamed protein product; Similar to the 2-hydroxy-6-ketonona-2,4-dienedoic acid hydrolase.
       0.524
plu2201
FAA_hydrolase domain-containing protein; Unnamed protein product; Similar to 2-oxopent-4-dienoate hydratase.
       0.422
tciR1
TciR1 protein; Similar to LysR-type transcriptional activator; Belongs to the LysR transcriptional regulatory family.
  
     0.415
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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