| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| dsdC | hcaR | plu1968 | plu2203 | D-serine dehydratase (deaminase) transcriptional activator DsdC; Belongs to the LysR transcriptional regulatory family. | Hca operon transcriptional activator; Belongs to the LysR transcriptional regulatory family. | 0.620 |
| hcaE | hcaR | plu2204 | plu2203 | 3-phenylpropionate dioxygenase alpha subunit (digoxigenin alpha subunit); Part of the multicomponent 3-phenylpropionate dioxygenase. Converts 3-phenylpropionic acid (PP) and cinnamic acid (CI) into 3- phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid- dihydrodiol (CI-dihydrodiol), respectively. | Hca operon transcriptional activator; Belongs to the LysR transcriptional regulatory family. | 0.595 |
| hcaE | plu2201 | plu2204 | plu2201 | 3-phenylpropionate dioxygenase alpha subunit (digoxigenin alpha subunit); Part of the multicomponent 3-phenylpropionate dioxygenase. Converts 3-phenylpropionic acid (PP) and cinnamic acid (CI) into 3- phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid- dihydrodiol (CI-dihydrodiol), respectively. | FAA_hydrolase domain-containing protein; Unnamed protein product; Similar to 2-oxopent-4-dienoate hydratase. | 0.794 |
| hcaE | plu2202 | plu2204 | plu2202 | 3-phenylpropionate dioxygenase alpha subunit (digoxigenin alpha subunit); Part of the multicomponent 3-phenylpropionate dioxygenase. Converts 3-phenylpropionic acid (PP) and cinnamic acid (CI) into 3- phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid- dihydrodiol (CI-dihydrodiol), respectively. | AB hydrolase-1 domain-containing protein; Unnamed protein product; Similar to the 2-hydroxy-6-ketonona-2,4-dienedoic acid hydrolase. | 0.802 |
| hcaR | dsdC | plu2203 | plu1968 | Hca operon transcriptional activator; Belongs to the LysR transcriptional regulatory family. | D-serine dehydratase (deaminase) transcriptional activator DsdC; Belongs to the LysR transcriptional regulatory family. | 0.620 |
| hcaR | hcaE | plu2203 | plu2204 | Hca operon transcriptional activator; Belongs to the LysR transcriptional regulatory family. | 3-phenylpropionate dioxygenase alpha subunit (digoxigenin alpha subunit); Part of the multicomponent 3-phenylpropionate dioxygenase. Converts 3-phenylpropionic acid (PP) and cinnamic acid (CI) into 3- phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid- dihydrodiol (CI-dihydrodiol), respectively. | 0.595 |
| hcaR | lrhA | plu2203 | plu3090 | Hca operon transcriptional activator; Belongs to the LysR transcriptional regulatory family. | LrhA (HexA) may be a general repressor of primary-specific phenotype. lrhA expression is increased (at least 10-fold) in the secondary variant of K122, UK210 and TT01; Belongs to the LysR transcriptional regulatory family. | 0.746 |
| hcaR | plu2201 | plu2203 | plu2201 | Hca operon transcriptional activator; Belongs to the LysR transcriptional regulatory family. | FAA_hydrolase domain-containing protein; Unnamed protein product; Similar to 2-oxopent-4-dienoate hydratase. | 0.422 |
| hcaR | plu2202 | plu2203 | plu2202 | Hca operon transcriptional activator; Belongs to the LysR transcriptional regulatory family. | AB hydrolase-1 domain-containing protein; Unnamed protein product; Similar to the 2-hydroxy-6-ketonona-2,4-dienedoic acid hydrolase. | 0.524 |
| hcaR | plu2641 | plu2203 | plu2641 | Hca operon transcriptional activator; Belongs to the LysR transcriptional regulatory family. | HTH lysR-type domain-containing protein; Unnamed protein product; Similar to transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family. | 0.744 |
| hcaR | plu2855 | plu2203 | plu2855 | Hca operon transcriptional activator; Belongs to the LysR transcriptional regulatory family. | HTH lysR-type domain-containing protein; Unnamed protein product; Highly similar to putative transcriptional regulator LysR-type YeiE of Escherichia coli; Belongs to the LysR transcriptional regulatory family. | 0.757 |
| hcaR | plu4133 | plu2203 | plu4133 | Hca operon transcriptional activator; Belongs to the LysR transcriptional regulatory family. | HTH lysR-type domain-containing protein; Unnamed protein product; Similar to transcription regulator, LysR family; Belongs to the LysR transcriptional regulatory family. | 0.734 |
| hcaR | plu4260 | plu2203 | plu4260 | Hca operon transcriptional activator; Belongs to the LysR transcriptional regulatory family. | HTH lysR-type domain-containing protein; Unnamed protein product; Similar to transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family. | 0.588 |
| hcaR | tciR1 | plu2203 | plu0966 | Hca operon transcriptional activator; Belongs to the LysR transcriptional regulatory family. | TciR1 protein; Similar to LysR-type transcriptional activator; Belongs to the LysR transcriptional regulatory family. | 0.415 |
| lrhA | hcaR | plu3090 | plu2203 | LrhA (HexA) may be a general repressor of primary-specific phenotype. lrhA expression is increased (at least 10-fold) in the secondary variant of K122, UK210 and TT01; Belongs to the LysR transcriptional regulatory family. | Hca operon transcriptional activator; Belongs to the LysR transcriptional regulatory family. | 0.746 |
| lrhA | plu2641 | plu3090 | plu2641 | LrhA (HexA) may be a general repressor of primary-specific phenotype. lrhA expression is increased (at least 10-fold) in the secondary variant of K122, UK210 and TT01; Belongs to the LysR transcriptional regulatory family. | HTH lysR-type domain-containing protein; Unnamed protein product; Similar to transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family. | 0.607 |
| lrhA | plu4133 | plu3090 | plu4133 | LrhA (HexA) may be a general repressor of primary-specific phenotype. lrhA expression is increased (at least 10-fold) in the secondary variant of K122, UK210 and TT01; Belongs to the LysR transcriptional regulatory family. | HTH lysR-type domain-containing protein; Unnamed protein product; Similar to transcription regulator, LysR family; Belongs to the LysR transcriptional regulatory family. | 0.603 |
| lrhA | plu4260 | plu3090 | plu4260 | LrhA (HexA) may be a general repressor of primary-specific phenotype. lrhA expression is increased (at least 10-fold) in the secondary variant of K122, UK210 and TT01; Belongs to the LysR transcriptional regulatory family. | HTH lysR-type domain-containing protein; Unnamed protein product; Similar to transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family. | 0.466 |
| plu2201 | hcaE | plu2201 | plu2204 | FAA_hydrolase domain-containing protein; Unnamed protein product; Similar to 2-oxopent-4-dienoate hydratase. | 3-phenylpropionate dioxygenase alpha subunit (digoxigenin alpha subunit); Part of the multicomponent 3-phenylpropionate dioxygenase. Converts 3-phenylpropionic acid (PP) and cinnamic acid (CI) into 3- phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid- dihydrodiol (CI-dihydrodiol), respectively. | 0.794 |
| plu2201 | hcaR | plu2201 | plu2203 | FAA_hydrolase domain-containing protein; Unnamed protein product; Similar to 2-oxopent-4-dienoate hydratase. | Hca operon transcriptional activator; Belongs to the LysR transcriptional regulatory family. | 0.422 |