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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hcaD3-phenylpropionate/cinnamic acid dioxygenase ferredoxin--NAD(+) reductase component; Part of the multicomponent 3-phenylpropionate dioxygenase, that converts 3-phenylpropionic acid (PP) and cinnamic acid (CI) into 3-phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid- dihydrodiol (CI-dihydrodiol), respectively. (394 aa)    
Predicted Functional Partners:
hcaC
3-phenylpropionate dioxygenase ferredoxin subunit (digoxigenin ferredoxin subunit); Part of the multicomponent 3-phenylpropionate dioxygenase, that converts 3-phenylpropionic acid (PP) and cinnamic acid (CI) into 3-phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid- dihydrodiol (CI-dihydrodiol), respectively. This protein seems to be a 2Fe-2S ferredoxin.
 
 0.978
hcaB
2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase; Converts 3-phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid-dihydrodiol (CI-dihydrodiol) into 3-(2,3- dihydroxylphenyl)propanoic acid (DHPP) and 2,3-dihydroxicinnamic acid (DHCI), respectively; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 0.968
hcaF
3-phenylpropionate dioxygenase beta subunit (digoxigenin beta subunit); Part of the multicomponent 3-phenylpropionate dioxygenase. Converts 3-phenylpropionic acid (PP) and cinnamic acid (CI) into 3- phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid- dihydrodiol (CI-dihydrodiol), respectively.
 
 
 0.960
hcaE
3-phenylpropionate dioxygenase alpha subunit (digoxigenin alpha subunit); Part of the multicomponent 3-phenylpropionate dioxygenase. Converts 3-phenylpropionic acid (PP) and cinnamic acid (CI) into 3- phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid- dihydrodiol (CI-dihydrodiol), respectively.
 
 0.956
plu2234
Unnamed protein product; Similar to histidine ammonia-lyase.
     
  0.900
plu1000
Rieske domain-containing protein; Unnamed protein product; Similar to salicylate-5-hydroxylase large oxygenase component.
  
 0.786
fdx
Ferredoxin, 2Fe-2S.
  
 
 0.701
plu2688
CopC domain-containing protein; Unnamed protein product; Similar to unknown protein YobA precursor of Escherichia coli.
  
 
   0.683
plu2262
Unnamed protein product; Some similarities with molybdopterin oxidoreductase and dimethylsulfoxide reductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
  
 
 0.682
hisI
phosphoribosyl-AMP cyclohydrolase (PRA-CH) / phosphoribosyl-ATP pyrophosphatase (PRA-PH); In the C-terminal section; belongs to the PRA-PH family.
  
    0.662
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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