Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mlcMaking large colonies protein. (403 aa)    
Predicted Functional Partners:
nagE
PTS system, N-acetylglucosamine-specific IIABC component (EIIABC-NAG) (N-acetylglucosamine-permease IIABC component) (Phosphotransferase enzyme II, ABC component) (EII-NAG).
  
 
 0.946
plu0585
Unnamed protein product; Similar to beta-glucoside permease IIABC component (phosphotransferase enzyme II, ABC component). Putative transmembrane protein.
  
 
 0.872
murP
N-acetylmuramic acid-specific phosphotransferase enzyme IIB component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in N-acetylmuramic acid (MurNAc) transport, yielding cytoplasmic MurNAc-6-P. Is also able to take up anhydro-N-acetylmuramic acid (anhMurNAc), but cannot phosphorylate the carbon 6, probably because of the 1,6-anhydro ring.
  
 
 0.770
bglF
Beta-glucoside-specific phosphotransferase system-dependent permease.
  
 
 0.770
plu1989
Unnamed protein product; Highly similar to phosphotransferase system enzyme II.
  
 
 0.770
treB
PTS system, trehalose-specific IIBC component (EIIBC-TRE) (trehalose-permease IIBC component) (phosphotransferase enzyme II, BC component) (EII-TRE).
  
 
 0.770
plu4229
MFS domain-containing protein; Unnamed protein product; Some similarities with multidrug-resistance protein. Putative transmembrane protein.
  
   
 0.602
gatY
Tagatose-bisphosphate aldolase GatY.
     
 0.575
plu0838
PTS EIIA type-4 domain-containing protein; Unnamed protein product; Similar to putative PTS system IIA component YadI of Escherichia coli.
     
 0.562
fruA
PTS system, fructose-specific IIBC component.
     
 0.561
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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