close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
plu2233Unnamed protein product; Similar to probable oxidoreductase YdfG of Escherichia coli; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (249 aa)    
Predicted Functional Partners:
plu1878
Carrier domain-containing protein; Unnamed protein product; Similar to antibiotic synthetase.
 
  
 0.936
plu2642
Carrier domain-containing protein; Unnamed protein product; Similar to proteins involved in antibiotic biosynthesis. Putative transmembrane protein.
 
  
 0.912
tdh
Threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family.
    
 0.903
plu1211
Carrier domain-containing protein; Unnamed protein product; Some similarities with lichenysin synthetase B, tyrocidine synthetase III, bacitracin synthetases and to other proteins involved in antibiotic synthesis.
      0.900
kbl
2-amino-3-ketobutyrate coenzyme A ligase (AKB ligase) (glycine acetyltransferase); Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
    
  0.900
plu0897
Carrier domain-containing protein; Unnamed protein product; Similar to peptide synthetases, pyoverdine synthetase and antibiotics synthetases; Belongs to the ATP-dependent AMP-binding enzyme family.
      0.800
plu3533
Carrier domain-containing protein; Unnamed protein product; Similar to proteins involved in antibiotics biosynthesis (NosC, gramidin S synthetase II, tyrocidine synthetase III...); Belongs to the ATP-dependent AMP-binding enzyme family.
 
  
 0.766
plu2234
Unnamed protein product; Similar to histidine ammonia-lyase.
     
 0.722
plu2231
Unnamed protein product; Similar to unknown protein YnfD precursor of Escherichia coli.
 
     0.594
gcvP
Glycine dehydrogenase [decarboxylating] (glycine decarboxylase) (glycine cleavage system P-protein); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
 
      0.591
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
Server load: low (24%) [HD]