STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
plu2353Hist_deacetyl domain-containing protein; Unnamed protein product; Highly similar to probable acetylpolyamine aminohydrolase. (370 aa)    
Predicted Functional Partners:
hepA
RNA polymerase associated protein (ATP-dependent helicase); Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
    
 0.800
htpG
Heat shock protein htpG (high temperature protein G) (heat shock protein C62.5); Molecular chaperone. Has ATPase activity.
    
 0.727
plu2475
Unnamed protein product; Similar to N-terminal region of WD-repeat protein, encoded by the toxC gene of Burkholderia glumae, involved in toxoflavin biosynthesis.
  
 
 0.663
ghrA
Glyoxylate/hydroxypyruvate reductase A; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
 
 
 0.578
gapA
Glyceraldehyde-3-phosphate dehydrogenase A (GAPDH-A); Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 
  
 0.569
plu2468
Unnamed protein product; Some similarities with unknown protein of Photorhabdus.
    
 0.566
plu4122
Unnamed protein product; Hypothetical gene.
    
 0.566
udk
Uridine kinase (uridine monophosphokinase) (pyrimidine ribonucleoside kinase).
   
 0.556
plu2704
SIR2_2 domain-containing protein; Unnamed protein product; Some similarities in N-terminal with unknown protein.
    
 
 0.476
cobB
CobB protein; Belongs to the sirtuin family. Class III subfamily.
    
 
 0.476
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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