Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
manAMannose-6-phosphate isomerase (phosphomannose isomerase) (phosphohexomutase) (PMI). (390 aa)    
Predicted Functional Partners:
manX
PTS system, mannose-specific IIAB component (EIIAB-MAN) (Mannose-permease IIAB component) (Phosphotransferase enzyme II, AB component) (EIII-MAN).
    
 0.948
pgi
Glucose-6-phosphate isomerase (GPI) (phosphoglucoseisomerase) (PGI) (phosphohexose isomerase) (PHI).
 
 
 0.940
glmS
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
     
 0.920
nagB
Glucosamine-6-phosphate isomerase (glucosamine6-phosphate deaminase) (GNPDA) (GLCN6P deaminase); Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
     
 0.917
pfkA
6-phosphofructokinase isozyme I (phosphofructokinase-1) (phosphohexokinase-1); Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
    
 0.914
manZ
PTS system, mannose-specific IID component (EIID-MAN) (Mannose-permease IID component) (Phosphotransferase enzyme II, D component) (EII-M-MAN).
    
 0.909
manY
PTS system, mannose-specific IIC component (EIIC-MAN) (Mannose-permease IIC component) (Phosphotransferase enzyme II, C component) (EII-P-MAN).
    
  0.906
fbp
Fructose-1,6-bisphosphatase (D-fructose-1,6-bisphosphate 1-phosphohydrolase) (FBPase).
     
 0.904
fruA
PTS system, fructose-specific IIBC component.
  
  
 0.802
tpiA
Triosephosphate isomerase (TIM); Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 
 0.671
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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