Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
cysBCys regulon transcriptional activator; Belongs to the LysR transcriptional regulatory family. (324 aa)    
Predicted Functional Partners:
pssR
Possible regulatory protein PssR; Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.
  
   
 0.720
plu0919
HTH luxR-type domain-containing protein; Unnamed protein product; Weakly similar to transcriptional regulator, LuxR family.
      
 0.623
plu2548
HTH lysR-type domain-containing protein; Unnamed protein product; Some similarities with transcription regulator LysR family; Belongs to the LysR transcriptional regulatory family.
      
 0.623
plu4185
HTH_11 domain-containing protein; Unnamed protein product; Some similarities with hypothetical proteins.
      
 0.623
plu0947
ABM domain-containing protein; Unnamed protein product; Similar to unknown protein.
      
 0.540
plu0948
HTH marR-type domain-containing protein; Unnamed protein product; Similar to transcriptional regulator.
      
 0.540
rpmE
50S ribosomal protein L31.
      
 0.539
glmS
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
      
 0.539
rpmE-2
50S ribosomal protein L31; Binds the 23S rRNA.
      
 0.539
topA
DNA topoisomerase I (omega protein) (relaxing enzyme) (untwisting enzyme) (swivelase); Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then un [...]
 
     0.518
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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