Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tpxThiol peroxidase (scavengase p20); Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily. (167 aa)    
Predicted Functional Partners:
sodA
Superoxide dismutase [Mn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
  
 0.770
zntB
Zinc transport protein ZntB; Mediates efflux of zinc ions; Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
  
    0.590
ahpC
Alkyl hydroperoxide reductase, small subunit (antioxidant).
  
  
 0.544
fur
Ferric uptake transcription regulator (ferric uptake regulator); Belongs to the Fur family.
   
  
 0.536
mppA
Periplasmic murein peptide-binding protein precursor.
       0.530
plu2233
Unnamed protein product; Similar to probable oxidoreductase YdfG of Escherichia coli; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
    0.528
minE
Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
   
    0.526
hmpA
Flavohemoprotein; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily.
      
 0.512
gor
Glutathione oxidoreductase (GR) (GRase).
  
  
 0.504
plu1266
Unnamed protein product; Highly similar to probable sigma-54 modulation protein YfiA of Escherichia coli.
   
    0.492
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.