| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| fruB | purR | plu1992 | plu2605 | PTS system, fructose-specific IIA/FPr component. | Purine nucleotide synthesis repressor protein PurR; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | 0.474 |
| gltB | plu1880 | plu4009 | plu1880 | Glutamate synthase [NADPH] large chain precursor (glutamate synthase alpha subunit) (NADPH-GOGAT) (GLTS alpha chain). | Unnamed protein product; Similar to proteins involved in antibiotic biosynthesis. Putative transmembrane protein. | 0.560 |
| gltB | purR | plu4009 | plu2605 | Glutamate synthase [NADPH] large chain precursor (glutamate synthase alpha subunit) (NADPH-GOGAT) (GLTS alpha chain). | Purine nucleotide synthesis repressor protein PurR; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | 0.693 |
| plu1880 | gltB | plu1880 | plu4009 | Unnamed protein product; Similar to proteins involved in antibiotic biosynthesis. Putative transmembrane protein. | Glutamate synthase [NADPH] large chain precursor (glutamate synthase alpha subunit) (NADPH-GOGAT) (GLTS alpha chain). | 0.560 |
| plu1880 | purR | plu1880 | plu2605 | Unnamed protein product; Similar to proteins involved in antibiotic biosynthesis. Putative transmembrane protein. | Purine nucleotide synthesis repressor protein PurR; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | 0.461 |
| purR | fruB | plu2605 | plu1992 | Purine nucleotide synthesis repressor protein PurR; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | PTS system, fructose-specific IIA/FPr component. | 0.474 |
| purR | gltB | plu2605 | plu4009 | Purine nucleotide synthesis repressor protein PurR; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | Glutamate synthase [NADPH] large chain precursor (glutamate synthase alpha subunit) (NADPH-GOGAT) (GLTS alpha chain). | 0.693 |
| purR | plu1880 | plu2605 | plu1880 | Purine nucleotide synthesis repressor protein PurR; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | Unnamed protein product; Similar to proteins involved in antibiotic biosynthesis. Putative transmembrane protein. | 0.461 |
| purR | rbsK | plu2605 | plu0059 | Purine nucleotide synthesis repressor protein PurR; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.415 |
| rbsK | purR | plu0059 | plu2605 | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | Purine nucleotide synthesis repressor protein PurR; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | 0.415 |