STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ppsAPhosphoenolpyruvate synthase (PEP synthase); Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (792 aa)    
Predicted Functional Partners:
maeB
NADP-dependent malic enzyme (NADP-ME).
  
 
 0.938
eno
Enolase (2-phosphoglycerate dehydratase) (2-phospho-D-glycerate hydro-lyase); Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
    
 0.921
plu2629
Putative phosphoenolpyruvate synthase regulatory protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
 
  
 0.920
pckA
Phosphoenolpyruvate carboxykinase [ATP]; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
     
 0.916
maeA
Malate dehydrogenase (oxaloacetate-decarboxylating); Belongs to the malic enzymes family.
   
 
 0.916
ldhA
D-lactate dehydrogenase (D-LDH); Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 0.916
ppc
Phosphoenolpyruvate carboxylase (PEPCASE) (PEPC); Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
     
 0.915
aceE
Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
     
 0.912
pflB
Formate acetyltransferase I (pyruvate formate-lyase 1).
    
 0.907
pykA
Pyruvate kinase II; Belongs to the pyruvate kinase family.
     
 0.907
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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