Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
hmuRHemin receptor precursor. (673 aa)    
Predicted Functional Partners:
plu2633
Unnamed protein product; Highly similar to hemin transport protein HemS/HmuS/ChuS.
 
   
 0.938
plu2634
Fe/B12 periplasmic-binding domain-containing protein; Unnamed protein product; Highly similar to hemin-binding protein.
 
  
 0.803
plu1880
Unnamed protein product; Similar to proteins involved in antibiotic biosynthesis. Putative transmembrane protein.
  
  
 0.773
tonB
TonB protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
  
 
 0.769
plu2631
Unnamed protein product; Some similarities with hemin uptake protein HemP.
  
  
 0.758
btuF
Vitamin B12 transport protein BtuF precursor; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC.
 
  
 0.750
hmuV
Hemin import ATP-binding protein HmuV; Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system.
 
   
 0.712
dppA
Periplasmic dipeptide transport protein precursor DppA.
  
   
 0.677
plu2321
Unnamed protein product; Similar to protein HMWP1 of Yersinia enterocolitica.
  
  
 0.647
plu2717
TonB_C domain-containing protein; Unnamed protein product; Similar to unknown protein CjrB of Escherichia coli O164 and some similarities with inner-membrane protein TonB.
 
 
 0.642
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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