| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| lolD | macB | plu2813 | plu1591 | Lipoprotein releasing system ATP-binding protein lolD; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. | Macrolide-specific ABC-type efflux carrier protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.528 |
| lolD | plu2647 | plu2813 | plu2647 | Lipoprotein releasing system ATP-binding protein lolD; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. | Unnamed protein product; Highly similar to permease of ABC transporter. | 0.824 |
| macA | macB | plu1590 | plu1591 | Macrolide-specific efflux protein MacA precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Macrolide-specific ABC-type efflux carrier protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.975 |
| macA | plu2645 | plu1590 | plu2645 | Macrolide-specific efflux protein MacA precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Unnamed protein product; Similar to Membrane Fusion Protein (MFP) of ABC transport system. | 0.600 |
| macA | plu2646 | plu1590 | plu2646 | Macrolide-specific efflux protein MacA precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Unnamed protein product; Similar to Outer Membrane Factor (OMF) of ABC transport system. | 0.491 |
| macA | plu2647 | plu1590 | plu2647 | Macrolide-specific efflux protein MacA precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Unnamed protein product; Highly similar to permease of ABC transporter. | 0.863 |
| macA | plu2648 | plu1590 | plu2648 | Macrolide-specific efflux protein MacA precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Unnamed protein product; Highly similar to ATP-binding component of ABC transporter. | 0.451 |
| macA | plu2735 | plu1590 | plu2735 | Macrolide-specific efflux protein MacA precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Unnamed protein product; Similar to ABC transporter (ATP-binding protein subunit). | 0.537 |
| macB | lolD | plu1591 | plu2813 | Macrolide-specific ABC-type efflux carrier protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | Lipoprotein releasing system ATP-binding protein lolD; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. | 0.528 |
| macB | macA | plu1591 | plu1590 | Macrolide-specific ABC-type efflux carrier protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | Macrolide-specific efflux protein MacA precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.975 |
| macB | plu0554 | plu1591 | plu0554 | Macrolide-specific ABC-type efflux carrier protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | Unnamed protein product; Similar to ABC transporter, ATP-binding protein. | 0.542 |
| macB | plu2645 | plu1591 | plu2645 | Macrolide-specific ABC-type efflux carrier protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | Unnamed protein product; Similar to Membrane Fusion Protein (MFP) of ABC transport system. | 0.656 |
| macB | plu2646 | plu1591 | plu2646 | Macrolide-specific ABC-type efflux carrier protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | Unnamed protein product; Similar to Outer Membrane Factor (OMF) of ABC transport system. | 0.796 |
| macB | plu2647 | plu1591 | plu2647 | Macrolide-specific ABC-type efflux carrier protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | Unnamed protein product; Highly similar to permease of ABC transporter. | 0.633 |
| macB | plu2648 | plu1591 | plu2648 | Macrolide-specific ABC-type efflux carrier protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | Unnamed protein product; Highly similar to ATP-binding component of ABC transporter. | 0.528 |
| macB | plu2734 | plu1591 | plu2734 | Macrolide-specific ABC-type efflux carrier protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | HlyD_D23 domain-containing protein; Unnamed protein product; Membrane fusion protein (MPF) component of efflux system; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.974 |
| macB | plu2735 | plu1591 | plu2735 | Macrolide-specific ABC-type efflux carrier protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | Unnamed protein product; Similar to ABC transporter (ATP-binding protein subunit). | 0.556 |
| plu0554 | macB | plu0554 | plu1591 | Unnamed protein product; Similar to ABC transporter, ATP-binding protein. | Macrolide-specific ABC-type efflux carrier protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.542 |
| plu0554 | plu2647 | plu0554 | plu2647 | Unnamed protein product; Similar to ABC transporter, ATP-binding protein. | Unnamed protein product; Highly similar to permease of ABC transporter. | 0.640 |
| plu2645 | macA | plu2645 | plu1590 | Unnamed protein product; Similar to Membrane Fusion Protein (MFP) of ABC transport system. | Macrolide-specific efflux protein MacA precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.600 |
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