| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| birA | fur | plu4732 | plu1327 | Bifunctional protein [Includes: biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Ferric uptake transcription regulator (ferric uptake regulator); Belongs to the Fur family. | 0.447 |
| birA | yfeA | plu4732 | plu2672 | Bifunctional protein [Includes: biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Iron (chelated) ABC transporter, periplasmic-binding protein YfeA; Belongs to the bacterial solute-binding protein 9 family. | 0.423 |
| birA | yfeB | plu4732 | plu2673 | Bifunctional protein [Includes: biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Iron transport system ATP-binding protein YfeB. | 0.400 |
| birA | zur | plu4732 | plu4373 | Bifunctional protein [Includes: biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Zinc uptake regulation protein (Zinc uptake regulator); Belongs to the Fur family. | 0.447 |
| fur | birA | plu1327 | plu4732 | Ferric uptake transcription regulator (ferric uptake regulator); Belongs to the Fur family. | Bifunctional protein [Includes: biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.447 |
| fur | yfeA | plu1327 | plu2672 | Ferric uptake transcription regulator (ferric uptake regulator); Belongs to the Fur family. | Iron (chelated) ABC transporter, periplasmic-binding protein YfeA; Belongs to the bacterial solute-binding protein 9 family. | 0.406 |
| fur | yfeB | plu1327 | plu2673 | Ferric uptake transcription regulator (ferric uptake regulator); Belongs to the Fur family. | Iron transport system ATP-binding protein YfeB. | 0.442 |
| fur | zur | plu1327 | plu4373 | Ferric uptake transcription regulator (ferric uptake regulator); Belongs to the Fur family. | Zinc uptake regulation protein (Zinc uptake regulator); Belongs to the Fur family. | 0.555 |
| yfeA | birA | plu2672 | plu4732 | Iron (chelated) ABC transporter, periplasmic-binding protein YfeA; Belongs to the bacterial solute-binding protein 9 family. | Bifunctional protein [Includes: biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.423 |
| yfeA | fur | plu2672 | plu1327 | Iron (chelated) ABC transporter, periplasmic-binding protein YfeA; Belongs to the bacterial solute-binding protein 9 family. | Ferric uptake transcription regulator (ferric uptake regulator); Belongs to the Fur family. | 0.406 |
| yfeA | yfeB | plu2672 | plu2673 | Iron (chelated) ABC transporter, periplasmic-binding protein YfeA; Belongs to the bacterial solute-binding protein 9 family. | Iron transport system ATP-binding protein YfeB. | 0.997 |
| yfeA | yfeC | plu2672 | plu2674 | Iron (chelated) ABC transporter, periplasmic-binding protein YfeA; Belongs to the bacterial solute-binding protein 9 family. | Chelated iron transport system membrane protein YfeC. | 0.997 |
| yfeA | yfeD | plu2672 | plu2675 | Iron (chelated) ABC transporter, periplasmic-binding protein YfeA; Belongs to the bacterial solute-binding protein 9 family. | Chelated iron transport system membrane protein yfeD homolog. | 0.996 |
| yfeA | znuB | plu2672 | plu2113 | Iron (chelated) ABC transporter, periplasmic-binding protein YfeA; Belongs to the bacterial solute-binding protein 9 family. | High-affinity zinc uptake system membrane protein ZnuB. | 0.876 |
| yfeA | zur | plu2672 | plu4373 | Iron (chelated) ABC transporter, periplasmic-binding protein YfeA; Belongs to the bacterial solute-binding protein 9 family. | Zinc uptake regulation protein (Zinc uptake regulator); Belongs to the Fur family. | 0.469 |
| yfeB | birA | plu2673 | plu4732 | Iron transport system ATP-binding protein YfeB. | Bifunctional protein [Includes: biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.400 |
| yfeB | fur | plu2673 | plu1327 | Iron transport system ATP-binding protein YfeB. | Ferric uptake transcription regulator (ferric uptake regulator); Belongs to the Fur family. | 0.442 |
| yfeB | yfeA | plu2673 | plu2672 | Iron transport system ATP-binding protein YfeB. | Iron (chelated) ABC transporter, periplasmic-binding protein YfeA; Belongs to the bacterial solute-binding protein 9 family. | 0.997 |
| yfeB | yfeC | plu2673 | plu2674 | Iron transport system ATP-binding protein YfeB. | Chelated iron transport system membrane protein YfeC. | 0.999 |
| yfeB | yfeD | plu2673 | plu2675 | Iron transport system ATP-binding protein YfeB. | Chelated iron transport system membrane protein yfeD homolog. | 0.993 |