| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| gppA | phoR | plu4666 | plu3910 | Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase; Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities. | Phosphate regulon sensor protein. | 0.400 |
| gppA | ppk | plu4666 | plu2763 | Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase; Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities. | Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. | 0.719 |
| gppA | ppx | plu4666 | plu2764 | Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase; Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities. | Exopolyphosphatase (exopolypase) (metaphosphatase); Belongs to the GppA/Ppx family. | 0.911 |
| hisD | ppk | plu1569 | plu2763 | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. | 0.401 |
| phoR | gppA | plu3910 | plu4666 | Phosphate regulon sensor protein. | Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase; Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities. | 0.400 |
| phoR | phoU | plu3910 | plu0218 | Phosphate regulon sensor protein. | Phosphate transport system protein PhoU; Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions. | 0.744 |
| phoR | ppk | plu3910 | plu2763 | Phosphate regulon sensor protein. | Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. | 0.492 |
| phoR | pstA | plu3910 | plu0216 | Phosphate regulon sensor protein. | Phosphate transport system permease protein PstA. | 0.602 |
| phoR | pstB | plu3910 | plu0217 | Phosphate regulon sensor protein. | Phosphate transport system permease protein PstB; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. | 0.692 |
| phoU | phoR | plu0218 | plu3910 | Phosphate transport system protein PhoU; Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions. | Phosphate regulon sensor protein. | 0.744 |
| phoU | ppk | plu0218 | plu2763 | Phosphate transport system protein PhoU; Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions. | Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. | 0.503 |
| phoU | pstA | plu0218 | plu0216 | Phosphate transport system protein PhoU; Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions. | Phosphate transport system permease protein PstA. | 0.981 |
| phoU | pstB | plu0218 | plu0217 | Phosphate transport system protein PhoU; Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions. | Phosphate transport system permease protein PstB; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. | 0.996 |
| ppa | ppk | plu4551 | plu2763 | Inorganic pyrophosphatase (pyrophosphate phospho-hydrolase) (PPase); Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions. | Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. | 0.940 |
| ppa | pstB | plu4551 | plu0217 | Inorganic pyrophosphatase (pyrophosphate phospho-hydrolase) (PPase); Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions. | Phosphate transport system permease protein PstB; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. | 0.493 |
| ppk | gppA | plu2763 | plu4666 | Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. | Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase; Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities. | 0.719 |
| ppk | hisD | plu2763 | plu1569 | Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.401 |
| ppk | phoR | plu2763 | plu3910 | Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. | Phosphate regulon sensor protein. | 0.492 |
| ppk | phoU | plu2763 | plu0218 | Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. | Phosphate transport system protein PhoU; Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions. | 0.503 |
| ppk | ppa | plu2763 | plu4551 | Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. | Inorganic pyrophosphatase (pyrophosphate phospho-hydrolase) (PPase); Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions. | 0.940 |