Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
plu2772A_deaminase domain-containing protein; Unnamed protein product; Similar to adenosine deaminase. (335 aa)    
Predicted Functional Partners:
add
Adenosine deaminase (adenosine aminohydrolase); Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
  
  
 
0.927
ushA
Protein UshA precursor [Includes: UDP-sugar hydrolase (UDP-sugar diphosphatase) (UDP-sugar pyrophosphatase); 5'-nucleotidase (5'-NT)]; Belongs to the 5'-nucleotidase family.
 
  
 0.917
cpdB
2',3'-cyclic-nucleotide 2'-phosphodiesterase precursor; Belongs to the 5'-nucleotidase family.
 
  
 0.917
deoD
Purine-nucleoside phosphorylase (inosine phosphorylase) (PNP).
    
 0.914
gsk
Inosine-guanosine kinase.
    
 0.911
iunH
Inosine-uridine preferring nucleoside hydrolase (IU-nucleoside hydrolase) (purine nucleosidase); Belongs to the IUNH family.
  
 
 0.910
surE
Acid phosphatase SurE (Stationary-phase survival protein SurE); Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs.
     
 0.904
plu1269
Polyphenol oxidase; Unnamed protein product; Highly similar to unknown protein YfiH of Escherichia coli; Belongs to the multicopper oxidase YfiH/RL5 family.
    
  0.901
plu3092
5'-deoxynucleotidase plu3092; Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates.
     
  0.900
plu2773
IU_nuc_hydro domain-containing protein; Unnamed protein product; Similar to nucleoside hydrolase.
  
  
 0.781
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.