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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mdtAMultidrug resistance protein MdtA; Unnamed protein product; Similar to putative membrane protein YegM of Escherichia coli; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (401 aa)    
Predicted Functional Partners:
mdtB
Multidrug resistance protein MdtB; Unnamed protein product; Highly similar to unknown protein YegN of Escherichia coli, putative acriflavin resistance protein D; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.
 
 0.942
mdtC
Multidrug resistance protein MdtC; Unnamed protein product; Highly similar to unknown protein YegO of Escherichia coli, putative acriflavin resistance protein F; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily.
 
 0.942
acrB
Acriflavin resistance protein B.
 
 0.921
plu0758
Unnamed protein product; Similar to multidrug efflux transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 0.914
macB
Macrolide-specific ABC-type efflux carrier protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.897
plu0759
HlyD_D23 domain-containing protein; Unnamed protein product; Some similarities with multidrug efflux membrane fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
   
 0.798
tolC
Outer membrane protein precursor TolC.
  
 
 0.716
baeS
Two-component sensor kinase.
  
  
 0.586
baeR
Two-component response regulator.
  
  
 0.564
acrR
acrAB operon repressor.
     
 0.534
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.