| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cspC | groES | plu2783 | plu4135 | Cold shock protein. | 10 kDa chaperonin (Protein CPN10) (Protein GROES); Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.612 |
| cspC | grpE | plu2783 | plu3372 | Cold shock protein. | GrpE protein (HSP-70 cofactor) (heat shock protein B25.3) (HSP24); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing [...] | 0.583 |
| cspC | rpsL | plu2783 | plu0429 | Cold shock protein. | Ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. | 0.431 |
| cspC | rpsQ | plu2783 | plu4717 | Cold shock protein. | 30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. | 0.424 |
| cspC | rpsS | plu2783 | plu4722 | Cold shock protein. | 30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. | 0.419 |
| cspC | rseA | plu2783 | plu3345 | Cold shock protein. | Sigma-E factor negative regulatory protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic p [...] | 0.591 |
| cspC | thiD | plu2783 | plu2782 | Cold shock protein. | Phosphomethylpyrimidine kinase (HMP-phosphate kinase). | 0.414 |
| groES | cspC | plu4135 | plu2783 | 10 kDa chaperonin (Protein CPN10) (Protein GROES); Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | Cold shock protein. | 0.612 |
| groES | grpE | plu4135 | plu3372 | 10 kDa chaperonin (Protein CPN10) (Protein GROES); Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | GrpE protein (HSP-70 cofactor) (heat shock protein B25.3) (HSP24); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing [...] | 0.986 |
| groES | rseA | plu4135 | plu3345 | 10 kDa chaperonin (Protein CPN10) (Protein GROES); Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | Sigma-E factor negative regulatory protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic p [...] | 0.576 |
| grpE | cspC | plu3372 | plu2783 | GrpE protein (HSP-70 cofactor) (heat shock protein B25.3) (HSP24); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing [...] | Cold shock protein. | 0.583 |
| grpE | groES | plu3372 | plu4135 | GrpE protein (HSP-70 cofactor) (heat shock protein B25.3) (HSP24); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing [...] | 10 kDa chaperonin (Protein CPN10) (Protein GROES); Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.986 |
| grpE | rseA | plu3372 | plu3345 | GrpE protein (HSP-70 cofactor) (heat shock protein B25.3) (HSP24); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing [...] | Sigma-E factor negative regulatory protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic p [...] | 0.581 |
| rpsL | cspC | plu0429 | plu2783 | Ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. | Cold shock protein. | 0.431 |
| rpsL | rpsQ | plu0429 | plu4717 | Ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. | 30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. | 0.998 |
| rpsL | rpsS | plu0429 | plu4722 | Ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. | 30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. | 0.999 |
| rpsQ | cspC | plu4717 | plu2783 | 30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. | Cold shock protein. | 0.424 |
| rpsQ | rpsL | plu4717 | plu0429 | 30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. | Ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. | 0.998 |
| rpsQ | rpsS | plu4717 | plu4722 | 30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. | 30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. | 0.999 |
| rpsS | cspC | plu4722 | plu2783 | 30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. | Cold shock protein. | 0.419 |
