Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
plu2795Transket_pyr domain-containing protein; Unnamed protein product; Similar to 3-methyl-2-oxobutanoate dehydrogenase (lipoamide). Putative transmembrane protein. (650 aa)    
Predicted Functional Partners:
plu1883
Transket_pyr domain-containing protein; Unnamed protein product; Similar to 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) alpha/beta E1 chain CP0743.
 
0.999
plu2796
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; Unnamed protein product; C terminal part similar to peptide synthetase. Putative transmembrane protein.
 
 0.998
lpdA
Dihydrolipoamide dehydrogenase (E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes) (glycine cleavage system L protein).
 
 0.998
plu1884
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; Unnamed protein product; Some similarities with dihydrolipoamide acyltransferase and succinyltransferase.
 
 0.996
sucB
Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex (E2); E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 
 0.995
aceF
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (E2); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.991
gor
Glutathione oxidoreductase (GR) (GRase).
 
 0.978
sthA
Soluble pyridine nucleotide transhydrogenase (STH) (NAD(P)(+) transhydrogenase [B-specific]); Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
 
 0.975
pflB
Formate acetyltransferase I (pyruvate formate-lyase 1).
   
 
 0.961
plu1438
Unnamed protein product; Similar to branched-chain amino acid aminotransferases.
  
 0.930
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
Server load: low (38%) [HD]