Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
plu2798Unnamed protein product; Similar to pteridine reductase 1 (H region methotrexate resistance protein). (254 aa)    
Predicted Functional Partners:
folA
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
     
 0.903
plu2075
Unnamed protein product; Similar to 3-oxoacyl-[acyl-carrier protein] reductase.
  
     0.718
plu2796
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; Unnamed protein product; C terminal part similar to peptide synthetase. Putative transmembrane protein.
  
 
 0.658
plu2797
Unnamed protein product; Hypothetical protein.
   
 
 0.652
nuoC
NADH dehydrogenase I chain C/D (NADH-ubiquinone oxidoreductase chain 3/4) (NUO3/NUO4); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
   
   0.636
plu2795
Transket_pyr domain-containing protein; Unnamed protein product; Similar to 3-methyl-2-oxobutanoate dehydrogenase (lipoamide). Putative transmembrane protein.
   
 
 0.628
plu2321
Unnamed protein product; Similar to protein HMWP1 of Yersinia enterocolitica.
  
 
 0.554
plu2799
HPPK domain-containing protein; Unnamed protein product; Some similarities with 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase.
       0.553
fabD
Malonyl CoA-acyl carrier protein transacylase (MCT).
 
 0.504
plu2450
Unnamed protein product; Highly similar to hypothetical oxidoreductase YciK of Escherichia coli.
  
     0.482
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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