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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
plu2799HPPK domain-containing protein; Unnamed protein product; Some similarities with 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase. (180 aa)    
Predicted Functional Partners:
folP
Dihydropteroate synthase (DHPS) (Dihydropteroate pyrophosphorylase); Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
 
 0.998
folB
Dihydroneopterin aldolase (DHNA); Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
 
 
 0.983
folK
7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase.
  
  
 
0.916
plu1369
Lactamase_B domain-containing protein; Unnamed protein product; Similar to metal-dependent hydrolases of the beta-lactamase superfamily II.
     
  0.900
plu2793
GTP_cyclohydroI domain-containing protein; Unnamed protein product; Some similarities with GTP cyclohydrolase I precursor.
 
  
 0.862
folE
GTP cyclohydrolase I (GTP-CH-I).
 
  
 0.840
plu3563
Glutamine amidotransferase type-1 domain-containing protein; Unnamed protein product; Similar to p-aminobenzoic acid synthase.
 
  
 0.673
pcnB
Poly(A) polymerase (PAP) (Plasmid copy number protein); Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
  
    0.598
folC
Dihydrofolate synthase/folylpolyglutamate synthase; Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10- formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.
 
  
 0.568
plu2798
Unnamed protein product; Similar to pteridine reductase 1 (H region methotrexate resistance protein).
       0.553
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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