| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| folP | metL | plu4534 | plu4755 | Dihydropteroate synthase (DHPS) (Dihydropteroate pyrophosphorylase); Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Bifunctional aspartokinase/homoserine dehydrogenase II (AKII-HDII) [Includes: Aspartokinase II; homoserine dehydrogenase II]; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.442 |
| folP | pabA | plu4534 | plu0393 | Dihydropteroate synthase (DHPS) (Dihydropteroate pyrophosphorylase); Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Para-aminobenzoate synthase glutamine amidotransferase, component II. | 0.548 |
| folP | pabB | plu4534 | plu2694 | Dihydropteroate synthase (DHPS) (Dihydropteroate pyrophosphorylase); Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | P-aminobenzoate synthase component I. | 0.486 |
| folP | pabC | plu4534 | plu2830 | Dihydropteroate synthase (DHPS) (Dihydropteroate pyrophosphorylase); Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 4-amino-4-deoxychorismate lyase (ADC lyase) (ADCL). | 0.932 |
| folP | plu3563 | plu4534 | plu3563 | Dihydropteroate synthase (DHPS) (Dihydropteroate pyrophosphorylase); Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Glutamine amidotransferase type-1 domain-containing protein; Unnamed protein product; Similar to p-aminobenzoic acid synthase. | 0.828 |
| folP | thrA | plu4534 | plu0563 | Dihydropteroate synthase (DHPS) (Dihydropteroate pyrophosphorylase); Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Aspartokinase I-homoserine dehydrogenase I; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.442 |
| holB | mltG | plu2827 | plu2829 | DNA-directed DNA polymerase III delta' chain. | Endolytic murein transglycosylase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. | 0.846 |
| holB | pabC | plu2827 | plu2830 | DNA-directed DNA polymerase III delta' chain. | 4-amino-4-deoxychorismate lyase (ADC lyase) (ADCL). | 0.699 |
| holB | tmk | plu2827 | plu2828 | DNA-directed DNA polymerase III delta' chain. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.926 |
| ilvD | metL | plu4682 | plu4755 | Dihydroxy-acid dehydratase (DAD); Belongs to the IlvD/Edd family. | Bifunctional aspartokinase/homoserine dehydrogenase II (AKII-HDII) [Includes: Aspartokinase II; homoserine dehydrogenase II]; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.704 |
| ilvD | pabC | plu4682 | plu2830 | Dihydroxy-acid dehydratase (DAD); Belongs to the IlvD/Edd family. | 4-amino-4-deoxychorismate lyase (ADC lyase) (ADCL). | 0.656 |
| ilvD | thrA | plu4682 | plu0563 | Dihydroxy-acid dehydratase (DAD); Belongs to the IlvD/Edd family. | Aspartokinase I-homoserine dehydrogenase I; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.704 |
| metL | folP | plu4755 | plu4534 | Bifunctional aspartokinase/homoserine dehydrogenase II (AKII-HDII) [Includes: Aspartokinase II; homoserine dehydrogenase II]; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Dihydropteroate synthase (DHPS) (Dihydropteroate pyrophosphorylase); Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.442 |
| metL | ilvD | plu4755 | plu4682 | Bifunctional aspartokinase/homoserine dehydrogenase II (AKII-HDII) [Includes: Aspartokinase II; homoserine dehydrogenase II]; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Dihydroxy-acid dehydratase (DAD); Belongs to the IlvD/Edd family. | 0.704 |
| metL | pabC | plu4755 | plu2830 | Bifunctional aspartokinase/homoserine dehydrogenase II (AKII-HDII) [Includes: Aspartokinase II; homoserine dehydrogenase II]; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 4-amino-4-deoxychorismate lyase (ADC lyase) (ADCL). | 0.609 |
| metL | plu3563 | plu4755 | plu3563 | Bifunctional aspartokinase/homoserine dehydrogenase II (AKII-HDII) [Includes: Aspartokinase II; homoserine dehydrogenase II]; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Glutamine amidotransferase type-1 domain-containing protein; Unnamed protein product; Similar to p-aminobenzoic acid synthase. | 0.452 |
| metL | thrA | plu4755 | plu0563 | Bifunctional aspartokinase/homoserine dehydrogenase II (AKII-HDII) [Includes: Aspartokinase II; homoserine dehydrogenase II]; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Aspartokinase I-homoserine dehydrogenase I; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.988 |
| metL | tmk | plu4755 | plu2828 | Bifunctional aspartokinase/homoserine dehydrogenase II (AKII-HDII) [Includes: Aspartokinase II; homoserine dehydrogenase II]; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.406 |
| mltG | holB | plu2829 | plu2827 | Endolytic murein transglycosylase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. | DNA-directed DNA polymerase III delta' chain. | 0.846 |
| mltG | pabC | plu2829 | plu2830 | Endolytic murein transglycosylase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. | 4-amino-4-deoxychorismate lyase (ADC lyase) (ADCL). | 0.710 |