| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cyaA | lapA | plu4643 | plu2429 | Adenylate cyclase (ATP pyrophosphate-lyase) (adenylyl cyclase); Belongs to the adenylyl cyclase class-1 family. | Lipopolysaccharide assembly protein A; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. | 0.766 |
| cyaA | lpp | plu4643 | plu2615 | Adenylate cyclase (ATP pyrophosphate-lyase) (adenylyl cyclase); Belongs to the adenylyl cyclase class-1 family. | Major outer membrane lipoprotein precursor (murein-lipoprotein); A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane. | 0.607 |
| cyaA | lptC | plu4643 | plu4038 | Adenylate cyclase (ATP pyrophosphate-lyase) (adenylyl cyclase); Belongs to the adenylyl cyclase class-1 family. | Lipopolysaccharide export system protein LptC; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | 0.614 |
| cyaA | ompN | plu4643 | plu1751 | Adenylate cyclase (ATP pyrophosphate-lyase) (adenylyl cyclase); Belongs to the adenylyl cyclase class-1 family. | Outer membrane protein N precursor (Porin OmpN). | 0.469 |
| cyaA | plu0668 | plu4643 | plu0668 | Adenylate cyclase (ATP pyrophosphate-lyase) (adenylyl cyclase); Belongs to the adenylyl cyclase class-1 family. | UPF0325 protein plu0668; Unnamed protein product; Highly similar to putative structural protein YaeH of Escherichia coli; Belongs to the UPF0325 family. | 0.618 |
| cyaA | plu1752 | plu4643 | plu1752 | Adenylate cyclase (ATP pyrophosphate-lyase) (adenylyl cyclase); Belongs to the adenylyl cyclase class-1 family. | Unnamed protein product; Highly similar to outer membrane protein N precursor (Porin OmpN); Belongs to the Gram-negative porin family. | 0.574 |
| cyaA | plu2843 | plu4643 | plu2843 | Adenylate cyclase (ATP pyrophosphate-lyase) (adenylyl cyclase); Belongs to the adenylyl cyclase class-1 family. | UPF0265 protein plu2843; Unnamed protein product; Highly similar to putative alpha helix protein, YeeX protein of Escherichia coli; Belongs to the UPF0265 family. | 0.714 |
| cyaA | plu4598 | plu4643 | plu4598 | Adenylate cyclase (ATP pyrophosphate-lyase) (adenylyl cyclase); Belongs to the adenylyl cyclase class-1 family. | Unnamed protein product; Highly similar to unknown protein YjeP precursor of Escherichia coli. | 0.468 |
| cyaA | viaA | plu4643 | plu0053 | Adenylate cyclase (ATP pyrophosphate-lyase) (adenylyl cyclase); Belongs to the adenylyl cyclase class-1 family. | Unnamed protein product; Similar to unknown protein YieM of Escherichia coli. | 0.638 |
| cyaA | zapB | plu4643 | plu4766 | Adenylate cyclase (ATP pyrophosphate-lyase) (adenylyl cyclase); Belongs to the adenylyl cyclase class-1 family. | Cell division protein ZapB; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA. | 0.714 |
| lapA | cyaA | plu2429 | plu4643 | Lipopolysaccharide assembly protein A; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. | Adenylate cyclase (ATP pyrophosphate-lyase) (adenylyl cyclase); Belongs to the adenylyl cyclase class-1 family. | 0.766 |
| lapA | lpp | plu2429 | plu2615 | Lipopolysaccharide assembly protein A; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. | Major outer membrane lipoprotein precursor (murein-lipoprotein); A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane. | 0.576 |
| lapA | lptC | plu2429 | plu4038 | Lipopolysaccharide assembly protein A; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. | Lipopolysaccharide export system protein LptC; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | 0.766 |
| lapA | ompN | plu2429 | plu1751 | Lipopolysaccharide assembly protein A; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. | Outer membrane protein N precursor (Porin OmpN). | 0.462 |
| lapA | plu0668 | plu2429 | plu0668 | Lipopolysaccharide assembly protein A; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. | UPF0325 protein plu0668; Unnamed protein product; Highly similar to putative structural protein YaeH of Escherichia coli; Belongs to the UPF0325 family. | 0.544 |
| lapA | plu1752 | plu2429 | plu1752 | Lipopolysaccharide assembly protein A; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. | Unnamed protein product; Highly similar to outer membrane protein N precursor (Porin OmpN); Belongs to the Gram-negative porin family. | 0.606 |
| lapA | plu2843 | plu2429 | plu2843 | Lipopolysaccharide assembly protein A; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. | UPF0265 protein plu2843; Unnamed protein product; Highly similar to putative alpha helix protein, YeeX protein of Escherichia coli; Belongs to the UPF0265 family. | 0.636 |
| lapA | plu4598 | plu2429 | plu4598 | Lipopolysaccharide assembly protein A; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. | Unnamed protein product; Highly similar to unknown protein YjeP precursor of Escherichia coli. | 0.436 |
| lapA | viaA | plu2429 | plu0053 | Lipopolysaccharide assembly protein A; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. | Unnamed protein product; Similar to unknown protein YieM of Escherichia coli. | 0.675 |
| lapA | zapB | plu2429 | plu4766 | Lipopolysaccharide assembly protein A; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. | Cell division protein ZapB; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA. | 0.725 |