Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fruK1-phosphofructokinase (fructose 1-phosphate kinase); Belongs to the carbohydrate kinase PfkB family. (312 aa)    
Predicted Functional Partners:
fruA
PTS system, fructose-specific IIBC component.
 
 
 0.999
fruB
PTS system, fructose-specific IIA/FPr component.
 
  
 0.986
pfkA
6-phosphofructokinase isozyme I (phosphofructokinase-1) (phosphohexokinase-1); Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
  
  
 0.945
fba
Fructose 1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
  
 
 0.938
fbaB
Fructose-biphosphate aldolase class I (FBP aldolase).
  
 
 0.925
fbp
Fructose-1,6-bisphosphatase (D-fructose-1,6-bisphosphate 1-phosphohydrolase) (FBPase).
    
 0.914
celC
PTS system, cellobiose-specific IIA component (EIIA-CEL) (Cellobiose-permease IIA component) (Phosphotransferase enzyme II, A component) (EIII-CEL).
  
  
 0.766
ptsN
Nitrogen regulatory IIA protein (enzyme IIA-NTR) (phosphotransferase enzyme II, A component).
 
  
 0.750
ptsI
Phosphoenolpyruvate-protein phosphotransferase (Phosphotransferase system, enzyme I); General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
  
 0.722
plu2511
HTH deoR-type domain-containing protein; Unnamed protein product; Highly similar to hypothetical transcriptional regulator YgbI of Escherichia coli.
 
  
 0.720
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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