STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
plu2965Unnamed protein product; Highly similar to the N-terminal region of siroheme synthase activity. (222 aa)    
Predicted Functional Partners:
plu2968
TP_methylase domain-containing protein; Unnamed protein product; Highly similar to the C-terminal region of siroheme synthase activity; Belongs to the precorrin methyltransferase family.
 
 0.999
cysG
Sirohaem synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
 
 
0.950
cbiF
Precorrin-4 C11-methyltransferase (precorrin-3-methylase).
   
 0.934
cbiL
Precorrin-2 C20-methyltransferase (S-adenosyl-L-methionine--precorrin-2 methyltransferase) (SP2MT); Belongs to the precorrin methyltransferase family.
    
 0.921
cbiK
Cobalt chelatase; Catalyzes the insertion of Co(2+) into sirohydrochlorin. Belongs to the CbiK family.
    
 0.911
hemX
uroporphyrin-III C-methyltransferase (urogen III methylase).
     
  0.900
plu2964
Corrinoid adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.
     
 0.795
plu2966
GHMP_kinases_N domain-containing protein; Unnamed protein product; Similar to PduX protein.
       0.788
cobD
Aminotransferase CobD.
     
 0.786
hemL
Glutamate-1-semialdehyde 2,1-aminomutase.
   
 0.593
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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