| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| btuR | cbiA | plu2451 | plu2999 | cob(I)alamin adenolsyltransferase (corrinoid adenosyltransferase); Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.944 |
| btuR | cbiB | plu2451 | plu2998 | cob(I)alamin adenolsyltransferase (corrinoid adenosyltransferase); Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | CbiB protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.960 |
| btuR | cbiP | plu2451 | plu2987 | cob(I)alamin adenolsyltransferase (corrinoid adenosyltransferase); Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.972 |
| btuR | cobS | plu2451 | plu2985 | cob(I)alamin adenolsyltransferase (corrinoid adenosyltransferase); Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | Cobalamin [5'-phosphate] synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.961 |
| btuR | cobU | plu2451 | plu2986 | cob(I)alamin adenolsyltransferase (corrinoid adenosyltransferase); Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | Bifunctional cobalamin biosynthesis protein cobU [Includes: Cobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.966 |
| btuR | plu2964 | plu2451 | plu2964 | cob(I)alamin adenolsyltransferase (corrinoid adenosyltransferase); Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | Corrinoid adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.903 |
| cbiA | btuR | plu2999 | plu2451 | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | cob(I)alamin adenolsyltransferase (corrinoid adenosyltransferase); Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.944 |
| cbiA | cbiB | plu2999 | plu2998 | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CbiB protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.981 |
| cbiA | cbiC | plu2999 | plu2997 | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Precorrin-8X methylmutase (Precorrin isomerase). | 0.998 |
| cbiA | cbiH | plu2999 | plu2991 | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Precorrin-3B C17-methyltransferase (precorrin-3 methyltransferase) (precorrin-3 methylase). | 0.970 |
| cbiA | cbiJ | plu2999 | plu2990 | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Precorrin-6X reductase. | 0.967 |
| cbiA | cbiL | plu2999 | plu2988 | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Precorrin-2 C20-methyltransferase (S-adenosyl-L-methionine--precorrin-2 methyltransferase) (SP2MT); Belongs to the precorrin methyltransferase family. | 0.961 |
| cbiA | cbiP | plu2999 | plu2987 | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.978 |
| cbiA | cobS | plu2999 | plu2985 | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Cobalamin [5'-phosphate] synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.898 |
| cbiA | cobU | plu2999 | plu2986 | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Bifunctional cobalamin biosynthesis protein cobU [Includes: Cobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.947 |
| cbiA | plu2964 | plu2999 | plu2964 | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Corrinoid adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.944 |
| cbiB | btuR | plu2998 | plu2451 | CbiB protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | cob(I)alamin adenolsyltransferase (corrinoid adenosyltransferase); Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.960 |
| cbiB | cbiA | plu2998 | plu2999 | CbiB protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.981 |
| cbiB | cbiC | plu2998 | plu2997 | CbiB protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | Precorrin-8X methylmutase (Precorrin isomerase). | 0.979 |
| cbiB | cbiH | plu2998 | plu2991 | CbiB protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | Precorrin-3B C17-methyltransferase (precorrin-3 methyltransferase) (precorrin-3 methylase). | 0.964 |