Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
nrdARibonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (763 aa)    
Predicted Functional Partners:
nrdB
Ribonucleoside-diphosphate reductase 1 beta chain (ribonucleotide reductase 1) (B2 protein) (R2 protein).
 
 0.999
nrdF
Ribonucleoside-diphosphate reductase 2 beta chain (ribonucleotide reductase 2) (R2f protein); Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.
  
 0.983
plu3054
2Fe-2S ferredoxin-type domain-containing protein; Unnamed protein product; Similar to ferredoxin-like protein YfaE of Escherichia coli.
 
  
 0.968
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
  
 
 0.932
mssA
Cytidylate kinase (CK) (cytidine monophosphate kinase) (CMP kinase) (MssA protein) (P25).
  
 
 0.921
plu0936
Thymidylate_kin domain-containing protein; Unnamed protein product; Some similarities with thymidylate kinase.
  
 
 0.917
adk
Adenylate kinase (ATP-AMP transphosphorylase); Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
    
 0.917
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
     
 0.905
plu2403
NDK domain-containing protein; Truncated gene. Highly similar to C-terminal region of transposase; Belongs to the NDK family.
     
 0.905
gmk
Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP.
     
 0.903
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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