| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| adk | gmk | plu3836 | plu0274 | Adenylate kinase (ATP-AMP transphosphorylase); Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | 0.643 |
| adk | mssA | plu3836 | plu1621 | Adenylate kinase (ATP-AMP transphosphorylase); Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Cytidylate kinase (CK) (cytidine monophosphate kinase) (CMP kinase) (MssA protein) (P25). | 0.524 |
| adk | ndk | plu3836 | plu1372 | Adenylate kinase (ATP-AMP transphosphorylase); Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.938 |
| adk | nrdA | plu3836 | plu3052 | Adenylate kinase (ATP-AMP transphosphorylase); Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.917 |
| adk | nrdB | plu3836 | plu3053 | Adenylate kinase (ATP-AMP transphosphorylase); Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Ribonucleoside-diphosphate reductase 1 beta chain (ribonucleotide reductase 1) (B2 protein) (R2 protein). | 0.916 |
| adk | nrdE | plu3836 | plu1285 | Adenylate kinase (ATP-AMP transphosphorylase); Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Ribonucleoside-diphosphate reductase alpha-chain (ribonucleotide reductase R1 subunit); Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.917 |
| adk | nrdF | plu3836 | plu1284 | Adenylate kinase (ATP-AMP transphosphorylase); Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Ribonucleoside-diphosphate reductase 2 beta chain (ribonucleotide reductase 2) (R2f protein); Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.916 |
| adk | tmk | plu3836 | plu2828 | Adenylate kinase (ATP-AMP transphosphorylase); Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.559 |
| gmk | adk | plu0274 | plu3836 | Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | Adenylate kinase (ATP-AMP transphosphorylase); Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.643 |
| gmk | mssA | plu0274 | plu1621 | Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | Cytidylate kinase (CK) (cytidine monophosphate kinase) (CMP kinase) (MssA protein) (P25). | 0.551 |
| gmk | ndk | plu0274 | plu1372 | Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.916 |
| gmk | nrdA | plu0274 | plu3052 | Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.903 |
| gmk | nrdB | plu0274 | plu3053 | Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | Ribonucleoside-diphosphate reductase 1 beta chain (ribonucleotide reductase 1) (B2 protein) (R2 protein). | 0.903 |
| gmk | nrdE | plu0274 | plu1285 | Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | Ribonucleoside-diphosphate reductase alpha-chain (ribonucleotide reductase R1 subunit); Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.903 |
| gmk | nrdF | plu0274 | plu1284 | Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | Ribonucleoside-diphosphate reductase 2 beta chain (ribonucleotide reductase 2) (R2f protein); Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.903 |
| gmk | tmk | plu0274 | plu2828 | Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.478 |
| mssA | adk | plu1621 | plu3836 | Cytidylate kinase (CK) (cytidine monophosphate kinase) (CMP kinase) (MssA protein) (P25). | Adenylate kinase (ATP-AMP transphosphorylase); Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.524 |
| mssA | gmk | plu1621 | plu0274 | Cytidylate kinase (CK) (cytidine monophosphate kinase) (CMP kinase) (MssA protein) (P25). | Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | 0.551 |
| mssA | ndk | plu1621 | plu1372 | Cytidylate kinase (CK) (cytidine monophosphate kinase) (CMP kinase) (MssA protein) (P25). | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.917 |
| mssA | nrdA | plu1621 | plu3052 | Cytidylate kinase (CK) (cytidine monophosphate kinase) (CMP kinase) (MssA protein) (P25). | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.921 |