Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
lrhALrhA (HexA) may be a general repressor of primary-specific phenotype. lrhA expression is increased (at least 10-fold) in the secondary variant of K122, UK210 and TT01; Belongs to the LysR transcriptional regulatory family. (309 aa)    
Predicted Functional Partners:
lrp
Leucine-responsive regulatory protein.
  
  
 0.839
lysR
Transcriptional activator protein LysR; Belongs to the LysR transcriptional regulatory family.
  
   
 0.766
hcaR
Hca operon transcriptional activator; Belongs to the LysR transcriptional regulatory family.
  
   
 0.759
plu4589
HTH lysR-type domain-containing protein; Unnamed protein product; Some similarities with transcription regulator LysR family homologs; Belongs to the LysR transcriptional regulatory family.
  
     0.712
plu1525
HTH lysR-type domain-containing protein; Unnamed protein product; Highly similar to LysR-family transcriptional regulator, YafC protein of Escherichia coli; Belongs to the LysR transcriptional regulatory family.
  
     0.703
rpoS
RNA polymerase sigma factor (sigma-38); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.
    
 
 0.697
abgR
Putative transcriptional regulator AbgR; Belongs to the LysR transcriptional regulatory family.
  
     0.697
rne
Ribonuclease E (RNase E); Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily.
   
 
 0.681
plu2792
HTH lysR-type domain-containing protein; Unnamed protein product; Similar to transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.670
plu3936
HTH lysR-type domain-containing protein; Unnamed protein product; Similar to LysR-family transcription regulators; Belongs to the LysR transcriptional regulatory family.
  
     0.670
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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