STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ackAAcetate kinase (acetokinase); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (400 aa)    
Predicted Functional Partners:
pta
Phosphate acetyltransferase (phosphotransacetylase); Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
 
 
 0.999
acs
Acetyl-coenzyme A synthetase (acetate--COA ligase) (acyl-activating enzyme); Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
     
 0.923
prpE
Propionate--CoA ligase (Propionyl-CoA synthetase).
     
 0.923
acyP
Acylphosphatase; Unnamed protein product; Similar to probable acylphosphatase YccX of Escherichia coli.
     
 0.918
plu0142
Aldedh domain-containing protein; Unnamed protein product; Similar to NADP-dependent aldehyde dehydrogenase.
    
 0.905
aldB
Aldehyde dehydrogenase B (Lactaldehyde dehydrogenase); Belongs to the aldehyde dehydrogenase family.
    
 0.905
maeB
NADP-dependent malic enzyme (NADP-ME).
 
  
 0.883
aceA
Isocitrate lyase (isocitrase) (isocitratase) (ICL).
   
  
 0.764
aceB
Malate synthase A (MSA).
   
  
 0.758
plu0585
Unnamed protein product; Similar to beta-glucoside permease IIABC component (phosphotransferase enzyme II, ABC component). Putative transmembrane protein.
     
 0.710
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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