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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hutHHistidine ammonia-lyase (histidase); Belongs to the PAL/histidase family. (514 aa)    
Predicted Functional Partners:
hutU
Urocanate hydratase (urocanase) (imidazolonepropionate hydrolase); Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.
 
 0.999
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
    
 0.945
hutI
Imidazolonepropionase (imidazolone-5-propionate hydrolase); Belongs to the metallo-dependent hydrolases superfamily. HutI family.
 
  
 0.940
hutC
Histidine utilization repressor protein.
 
  
 0.733
hutG
Formiminoglutamase (formiminoglutamate hydrolase) (histidine utilization repressor G) (fragment); Catalyzes the conversion of N-formimidoyl-L-glutamate to L- glutamate and formamide; Belongs to the arginase family.
 
  
 0.704
plu3191
AA_permease domain-containing protein; Unnamed protein product; Highly similar to amino acid permease (proline-specific permease ProY of Escherichia coli).
  
  
 0.583
chb
Chitobiase precursor (N-acetyl-beta-glucosaminidase)-beta-N- acetylhexosaminidase).
   
    0.555
pepD
Aminoacyl-histidine dipeptidase (XAA-His dipeptidase) (beta-alanyl-histidine dipeptidase) (carnosinase) (peptidase D).
     
 0.524
hisB
Histidinol-phosphatase/imisazoleglycerol- phosphate dehydratase; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
     
 0.478
gcvP
Glycine dehydrogenase [decarboxylating] (glycine decarboxylase) (glycine cleavage system P-protein); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
  
 0.475
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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