Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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yfhDPutative periplasmic binding transport protein YfhD; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella. (448 aa)    
Predicted Functional Partners:
purL
Phosphoribosylformylglycineamide synthetase (formylglycineamide ribonucleotide synthetase); Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
     
 0.724
mltD
Membrane-bound lytic murein transglycosylase D precursor (murein hydrolase D).
 
   
 0.532
lolB
Outer-membrane lipoprotein LolB precursor; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
 
     0.530
adiA
Biodegradative arginine decarboxylase.
       0.501
hemY
HemY protein; Involved in a late step of protoheme IX synthesis.
  
   
 0.491
ftsL
Cell division protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
  
   
 0.488
plu0941
Methyltransf_11 domain-containing protein; Unnamed protein product; Similar to unknown protein YafS of Escherichia coli.
  
     0.487
nudJ
Phosphatase NudJ; Unnamed protein product; Similar to probable dNTP pyrophosphohydrolase YmfB of Escherichia coli; Belongs to the Nudix hydrolase family. NudJ subfamily.
  
     0.454
tadA
tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
     
 0.435
rseB
Sigma-E factor regulatory protein RseB precursor.
  
     0.419
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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