| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| degS | rseA | plu4022 | plu3345 | Protease DegS; Truncated gene, similar to virulence-associated protein. | Sigma-E factor negative regulatory protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic p [...] | 0.846 |
| fecI | plu1235 | plu4444 | plu1235 | RNA polymerase sigma factor; Truncated transposase, IS30 family (ISPlu1-p); Belongs to the sigma-70 factor family. ECF subfamily. | Unnamed protein product; Similar to sigma-70 factor, ECF subfamily. | 0.910 |
| fecI | rseA | plu4444 | plu3345 | RNA polymerase sigma factor; Truncated transposase, IS30 family (ISPlu1-p); Belongs to the sigma-70 factor family. ECF subfamily. | Sigma-E factor negative regulatory protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic p [...] | 0.751 |
| lapA | lptC | plu2429 | plu4038 | Lipopolysaccharide assembly protein A; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. | Lipopolysaccharide export system protein LptC; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | 0.766 |
| lapA | nlpB | plu2429 | plu2745 | Lipopolysaccharide assembly protein A; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. | Lipoprotein-34 precursor; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.733 |
| lapA | rseA | plu2429 | plu3345 | Lipopolysaccharide assembly protein A; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. | Sigma-E factor negative regulatory protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic p [...] | 0.770 |
| lapA | rseB | plu2429 | plu3344 | Lipopolysaccharide assembly protein A; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. | Sigma-E factor regulatory protein RseB precursor. | 0.609 |
| lptC | lapA | plu4038 | plu2429 | Lipopolysaccharide export system protein LptC; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | Lipopolysaccharide assembly protein A; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. | 0.766 |
| lptC | nlpB | plu4038 | plu2745 | Lipopolysaccharide export system protein LptC; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | Lipoprotein-34 precursor; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.759 |
| lptC | rseA | plu4038 | plu3345 | Lipopolysaccharide export system protein LptC; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | Sigma-E factor negative regulatory protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic p [...] | 0.755 |
| lptC | rseB | plu4038 | plu3344 | Lipopolysaccharide export system protein LptC; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | Sigma-E factor regulatory protein RseB precursor. | 0.620 |
| nlpB | lapA | plu2745 | plu2429 | Lipoprotein-34 precursor; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Lipopolysaccharide assembly protein A; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. | 0.733 |
| nlpB | lptC | plu2745 | plu4038 | Lipoprotein-34 precursor; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Lipopolysaccharide export system protein LptC; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | 0.759 |
| nlpB | rseA | plu2745 | plu3345 | Lipoprotein-34 precursor; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Sigma-E factor negative regulatory protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic p [...] | 0.754 |
| nlpB | rseB | plu2745 | plu3344 | Lipoprotein-34 precursor; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Sigma-E factor regulatory protein RseB precursor. | 0.588 |
| plu0077 | rseA | plu0077 | plu3345 | Unnamed protein product; Similar to transcription initiation factor sigma homolog; Belongs to the sigma-70 factor family. ECF subfamily. | Sigma-E factor negative regulatory protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic p [...] | 0.751 |
| plu0741 | rseA | plu0741 | plu3345 | Unnamed protein product; Similar to probable sigma-70 factor, ECF subfamily. | Sigma-E factor negative regulatory protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic p [...] | 0.751 |
| plu1235 | fecI | plu1235 | plu4444 | Unnamed protein product; Similar to sigma-70 factor, ECF subfamily. | RNA polymerase sigma factor; Truncated transposase, IS30 family (ISPlu1-p); Belongs to the sigma-70 factor family. ECF subfamily. | 0.910 |
| plu1235 | rseA | plu1235 | plu3345 | Unnamed protein product; Similar to sigma-70 factor, ECF subfamily. | Sigma-E factor negative regulatory protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic p [...] | 0.751 |
| rpoE | rseA | plu3346 | plu3345 | RNA polymerase sigma-E factor (sigma-24); Belongs to the sigma-70 factor family. ECF subfamily. | Sigma-E factor negative regulatory protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic p [...] | 0.970 |