Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rseASigma-E factor negative regulatory protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic p [...] (216 aa)    
Predicted Functional Partners:
rseB
Sigma-E factor regulatory protein RseB precursor.
 
 
 0.996
rpoE
RNA polymerase sigma-E factor (sigma-24); Belongs to the sigma-70 factor family. ECF subfamily.
  
 
 0.985
degS
Protease DegS; Truncated gene, similar to virulence-associated protein.
  
 
 0.962
rseC
Sigma-E factor regulatory protein RseC.
 
  
 0.828
degQ
Protease precursor DegQ; Belongs to the peptidase S1C family.
  
 
 0.828
plu0077
Unnamed protein product; Similar to transcription initiation factor sigma homolog; Belongs to the sigma-70 factor family. ECF subfamily.
  
 
 0.820
plu0741
Unnamed protein product; Similar to probable sigma-70 factor, ECF subfamily.
  
 
 0.820
plu1235
Unnamed protein product; Similar to sigma-70 factor, ECF subfamily.
  
 
 0.820
fecI
RNA polymerase sigma factor; Truncated transposase, IS30 family (ISPlu1-p); Belongs to the sigma-70 factor family. ECF subfamily.
  
 
 0.820
lapA
Lipopolysaccharide assembly protein A; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family.
  
     0.770
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
Server load: low (20%) [HD]