| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| degQ | rseA | plu4018 | plu3345 | Protease precursor DegQ; Belongs to the peptidase S1C family. | Sigma-E factor negative regulatory protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic p [...] | 0.828 |
| degS | rseA | plu4022 | plu3345 | Protease DegS; Truncated gene, similar to virulence-associated protein. | Sigma-E factor negative regulatory protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic p [...] | 0.962 |
| fecI | plu1235 | plu4444 | plu1235 | RNA polymerase sigma factor; Truncated transposase, IS30 family (ISPlu1-p); Belongs to the sigma-70 factor family. ECF subfamily. | Unnamed protein product; Similar to sigma-70 factor, ECF subfamily. | 0.910 |
| fecI | rseA | plu4444 | plu3345 | RNA polymerase sigma factor; Truncated transposase, IS30 family (ISPlu1-p); Belongs to the sigma-70 factor family. ECF subfamily. | Sigma-E factor negative regulatory protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic p [...] | 0.820 |
| lapA | rseA | plu2429 | plu3345 | Lipopolysaccharide assembly protein A; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. | Sigma-E factor negative regulatory protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic p [...] | 0.770 |
| lapA | rseB | plu2429 | plu3344 | Lipopolysaccharide assembly protein A; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. | Sigma-E factor regulatory protein RseB precursor. | 0.609 |
| plu0077 | rseA | plu0077 | plu3345 | Unnamed protein product; Similar to transcription initiation factor sigma homolog; Belongs to the sigma-70 factor family. ECF subfamily. | Sigma-E factor negative regulatory protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic p [...] | 0.820 |
| plu0741 | rseA | plu0741 | plu3345 | Unnamed protein product; Similar to probable sigma-70 factor, ECF subfamily. | Sigma-E factor negative regulatory protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic p [...] | 0.820 |
| plu1235 | fecI | plu1235 | plu4444 | Unnamed protein product; Similar to sigma-70 factor, ECF subfamily. | RNA polymerase sigma factor; Truncated transposase, IS30 family (ISPlu1-p); Belongs to the sigma-70 factor family. ECF subfamily. | 0.910 |
| plu1235 | rseA | plu1235 | plu3345 | Unnamed protein product; Similar to sigma-70 factor, ECF subfamily. | Sigma-E factor negative regulatory protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic p [...] | 0.820 |
| rpoE | rseA | plu3346 | plu3345 | RNA polymerase sigma-E factor (sigma-24); Belongs to the sigma-70 factor family. ECF subfamily. | Sigma-E factor negative regulatory protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic p [...] | 0.985 |
| rpoE | rseB | plu3346 | plu3344 | RNA polymerase sigma-E factor (sigma-24); Belongs to the sigma-70 factor family. ECF subfamily. | Sigma-E factor regulatory protein RseB precursor. | 0.651 |
| rseA | degQ | plu3345 | plu4018 | Sigma-E factor negative regulatory protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic p [...] | Protease precursor DegQ; Belongs to the peptidase S1C family. | 0.828 |
| rseA | degS | plu3345 | plu4022 | Sigma-E factor negative regulatory protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic p [...] | Protease DegS; Truncated gene, similar to virulence-associated protein. | 0.962 |
| rseA | fecI | plu3345 | plu4444 | Sigma-E factor negative regulatory protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic p [...] | RNA polymerase sigma factor; Truncated transposase, IS30 family (ISPlu1-p); Belongs to the sigma-70 factor family. ECF subfamily. | 0.820 |
| rseA | lapA | plu3345 | plu2429 | Sigma-E factor negative regulatory protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic p [...] | Lipopolysaccharide assembly protein A; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. | 0.770 |
| rseA | plu0077 | plu3345 | plu0077 | Sigma-E factor negative regulatory protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic p [...] | Unnamed protein product; Similar to transcription initiation factor sigma homolog; Belongs to the sigma-70 factor family. ECF subfamily. | 0.820 |
| rseA | plu0741 | plu3345 | plu0741 | Sigma-E factor negative regulatory protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic p [...] | Unnamed protein product; Similar to probable sigma-70 factor, ECF subfamily. | 0.820 |
| rseA | plu1235 | plu3345 | plu1235 | Sigma-E factor negative regulatory protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic p [...] | Unnamed protein product; Similar to sigma-70 factor, ECF subfamily. | 0.820 |
| rseA | rpoE | plu3345 | plu3346 | Sigma-E factor negative regulatory protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic p [...] | RNA polymerase sigma-E factor (sigma-24); Belongs to the sigma-70 factor family. ECF subfamily. | 0.985 |