STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prpD2-methylcitrate dehydratase. (483 aa)    
Predicted Functional Partners:
prpC
2-methylcitrate synthase (Methylcitrate synthase) (Citrate synthase 2); Belongs to the citrate synthase family.
 
 0.997
prpB
Probable methylisocitrate lyase (2-methylisocitrate lyase); Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
 
  
 0.958
acnB
Aconitate hydratase 2 (citrate hydro-lyase 2) (aconitase 2); Belongs to the aconitase/IPM isomerase family.
     
 0.917
plu1865
Unnamed protein product; Truncated gene. Some similarities with putative phosphoenolpyruvate phosphomutase.
 
  
 0.831
prpE
Propionate--CoA ligase (Propionyl-CoA synthetase).
  
  
 0.715
acnA
Aconitate hydratase 1 (citrate hydro-lyase 1) (aconitase 1); Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
  
 
 0.675
gltA
Citrate synthase; Belongs to the citrate synthase family.
 
  
 0.652
plu3138
Citrate synthase; Unnamed protein product; Weakly similar to citrate synthase.
 
  
 0.652
prpR
Propionate catabolism operon regulatory protein.
     
 0.420
plu2325
Unnamed protein product; Similar to oxalate decarboxylase OxdC protein of Bacillus subtilis.
  
     0.400
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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