Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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Score
pepPXaa-Pro aminopeptidase (X-Pro aminopeptidase) (aminopeptidase P II) (APP-II) (aminoacylproline aminopeptidase). (438 aa)    
Predicted Functional Partners:
ubiH
2-octaprenyl-6-methoxyphenol hydroxylase.
  
  
 0.799
visC
Probable monooxygenase VisC.
  
  
 0.733
plu3602
UPF0149 protein plu3602; Unnamed protein product; Similar to unknown protein YgfB of Escherichia coli; Belongs to the UPF0149 family.
     
 0.686
plu3603
Cell division protein ZapA; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
     
 0.590
gcvP
Glycine dehydrogenase [decarboxylating] (glycine decarboxylase) (glycine cleavage system P-protein); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
  
  
 0.560
trpC
Tryptophan biosynthesis protein TrpCF [includes: indole-3-glycerol phosphate synthase (IGPS); N-(5'-phospho-ribosyl)anthrnilate isomerase (PRAI)].
  
  
 0.490
gcvT
Aminomethyltransferase (glycine cleavage system T protein); The glycine cleavage system catalyzes the degradation of glycine.
  
 
 0.466
hemF
Oxygen-dependent coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.
 
   
 0.458
gltB
Glutamate synthase [NADPH] large chain precursor (glutamate synthase alpha subunit) (NADPH-GOGAT) (GLTS alpha chain).
       0.410
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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