Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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plu3603Cell division protein ZapA; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division. (109 aa)    
Predicted Functional Partners:
ubiH
2-octaprenyl-6-methoxyphenol hydroxylase.
     
 0.782
ihfA
Integration host factor alpha chain (IHF-alpha); This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.
  
    0.769
visC
Probable monooxygenase VisC.
     
 0.769
rpiA
Ribose 5-phosphate isomerase A (phosphoriboisomerase A); Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
     
 0.758
plu3602
UPF0149 protein plu3602; Unnamed protein product; Similar to unknown protein YgfB of Escherichia coli; Belongs to the UPF0149 family.
  
  
 0.719
hemD
Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
  
    0.710
ubiE
Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).
      
 0.704
plu3604
5-formyltetrahydrofolate cyclo-ligase; Unnamed protein product; Similar to putative ligase YgfA of Escherichia coli; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.
     
 0.680
zapB
Cell division protein ZapB; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.
  
 
 0.662
plu1264
HNS domain-containing protein; Unnamed protein product; Similar to the DNA-binding protein H-NS (protein H1 or B1).
  
    0.660
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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