| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| argO | iciA | plu3612 | plu3610 | Arginine exporter protein ArgO; Involved in the export of arginine. Important to control the intracellular level of arginine and the correct balance between arginine and lysine; Belongs to the LysE/ArgO transporter (TC 2.A.75) family. | Chromosome initiation inhibitor (OriC replication inhibitor); Controls the transcription of genes involved in arginine and lysine metabolism; Belongs to the LysR transcriptional regulatory family. | 0.878 |
| dnaQ | iciA | plu0943 | plu3610 | DNA polymerase III epsilon chain; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | Chromosome initiation inhibitor (OriC replication inhibitor); Controls the transcription of genes involved in arginine and lysine metabolism; Belongs to the LysR transcriptional regulatory family. | 0.484 |
| eda | iciA | plu0178 | plu3610 | KHG/KDPG aldolase [Includes: 4-hydroxy-2-oxoglutarate ldolase (2-keto-4-hydroxyglutarate aldolase) (KHG-aldolase); 2-dehydro-3-deoxyphosphogluconate aldolase (Phospho-2-dehydro-3-deoxygluconate aldolase) (Phospho-2-keto-3-deoxygluconate aldolase) (2-keto-3-deoxy-6-phosphogluconate aldolase) (KDPG-aldolase)]. | Chromosome initiation inhibitor (OriC replication inhibitor); Controls the transcription of genes involved in arginine and lysine metabolism; Belongs to the LysR transcriptional regulatory family. | 0.513 |
| eda | phoB | plu0178 | plu3911 | KHG/KDPG aldolase [Includes: 4-hydroxy-2-oxoglutarate ldolase (2-keto-4-hydroxyglutarate aldolase) (KHG-aldolase); 2-dehydro-3-deoxyphosphogluconate aldolase (Phospho-2-dehydro-3-deoxygluconate aldolase) (Phospho-2-keto-3-deoxygluconate aldolase) (2-keto-3-deoxy-6-phosphogluconate aldolase) (KDPG-aldolase)]. | Phosphate regulon transcriptional regulatory protein. | 0.497 |
| gltB | iciA | plu4009 | plu3610 | Glutamate synthase [NADPH] large chain precursor (glutamate synthase alpha subunit) (NADPH-GOGAT) (GLTS alpha chain). | Chromosome initiation inhibitor (OriC replication inhibitor); Controls the transcription of genes involved in arginine and lysine metabolism; Belongs to the LysR transcriptional regulatory family. | 0.450 |
| iciA | argO | plu3610 | plu3612 | Chromosome initiation inhibitor (OriC replication inhibitor); Controls the transcription of genes involved in arginine and lysine metabolism; Belongs to the LysR transcriptional regulatory family. | Arginine exporter protein ArgO; Involved in the export of arginine. Important to control the intracellular level of arginine and the correct balance between arginine and lysine; Belongs to the LysE/ArgO transporter (TC 2.A.75) family. | 0.878 |
| iciA | dnaQ | plu3610 | plu0943 | Chromosome initiation inhibitor (OriC replication inhibitor); Controls the transcription of genes involved in arginine and lysine metabolism; Belongs to the LysR transcriptional regulatory family. | DNA polymerase III epsilon chain; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | 0.484 |
| iciA | eda | plu3610 | plu0178 | Chromosome initiation inhibitor (OriC replication inhibitor); Controls the transcription of genes involved in arginine and lysine metabolism; Belongs to the LysR transcriptional regulatory family. | KHG/KDPG aldolase [Includes: 4-hydroxy-2-oxoglutarate ldolase (2-keto-4-hydroxyglutarate aldolase) (KHG-aldolase); 2-dehydro-3-deoxyphosphogluconate aldolase (Phospho-2-dehydro-3-deoxygluconate aldolase) (Phospho-2-keto-3-deoxygluconate aldolase) (2-keto-3-deoxy-6-phosphogluconate aldolase) (KDPG-aldolase)]. | 0.513 |
| iciA | gltB | plu3610 | plu4009 | Chromosome initiation inhibitor (OriC replication inhibitor); Controls the transcription of genes involved in arginine and lysine metabolism; Belongs to the LysR transcriptional regulatory family. | Glutamate synthase [NADPH] large chain precursor (glutamate synthase alpha subunit) (NADPH-GOGAT) (GLTS alpha chain). | 0.450 |
| iciA | phoB | plu3610 | plu3911 | Chromosome initiation inhibitor (OriC replication inhibitor); Controls the transcription of genes involved in arginine and lysine metabolism; Belongs to the LysR transcriptional regulatory family. | Phosphate regulon transcriptional regulatory protein. | 0.504 |
| iciA | plu3608 | plu3610 | plu3608 | Chromosome initiation inhibitor (OriC replication inhibitor); Controls the transcription of genes involved in arginine and lysine metabolism; Belongs to the LysR transcriptional regulatory family. | Unnamed protein product; Similar to unknown protein of Photorhabdus. | 0.408 |
| iciA | plu3609 | plu3610 | plu3609 | Chromosome initiation inhibitor (OriC replication inhibitor); Controls the transcription of genes involved in arginine and lysine metabolism; Belongs to the LysR transcriptional regulatory family. | Unnamed protein product; Hypothetical gene. | 0.553 |
| iciA | rdgC | plu3610 | plu3929 | Chromosome initiation inhibitor (OriC replication inhibitor); Controls the transcription of genes involved in arginine and lysine metabolism; Belongs to the LysR transcriptional regulatory family. | Recombinaison associated protein; May be involved in recombination; Belongs to the RdgC family. | 0.466 |
| phoB | eda | plu3911 | plu0178 | Phosphate regulon transcriptional regulatory protein. | KHG/KDPG aldolase [Includes: 4-hydroxy-2-oxoglutarate ldolase (2-keto-4-hydroxyglutarate aldolase) (KHG-aldolase); 2-dehydro-3-deoxyphosphogluconate aldolase (Phospho-2-dehydro-3-deoxygluconate aldolase) (Phospho-2-keto-3-deoxygluconate aldolase) (2-keto-3-deoxy-6-phosphogluconate aldolase) (KDPG-aldolase)]. | 0.497 |
| phoB | iciA | plu3911 | plu3610 | Phosphate regulon transcriptional regulatory protein. | Chromosome initiation inhibitor (OriC replication inhibitor); Controls the transcription of genes involved in arginine and lysine metabolism; Belongs to the LysR transcriptional regulatory family. | 0.504 |
| plu3608 | iciA | plu3608 | plu3610 | Unnamed protein product; Similar to unknown protein of Photorhabdus. | Chromosome initiation inhibitor (OriC replication inhibitor); Controls the transcription of genes involved in arginine and lysine metabolism; Belongs to the LysR transcriptional regulatory family. | 0.408 |
| plu3608 | plu3609 | plu3608 | plu3609 | Unnamed protein product; Similar to unknown protein of Photorhabdus. | Unnamed protein product; Hypothetical gene. | 0.553 |
| plu3609 | iciA | plu3609 | plu3610 | Unnamed protein product; Hypothetical gene. | Chromosome initiation inhibitor (OriC replication inhibitor); Controls the transcription of genes involved in arginine and lysine metabolism; Belongs to the LysR transcriptional regulatory family. | 0.553 |
| plu3609 | plu3608 | plu3609 | plu3608 | Unnamed protein product; Hypothetical gene. | Unnamed protein product; Similar to unknown protein of Photorhabdus. | 0.553 |
| rdgC | iciA | plu3929 | plu3610 | Recombinaison associated protein; May be involved in recombination; Belongs to the RdgC family. | Chromosome initiation inhibitor (OriC replication inhibitor); Controls the transcription of genes involved in arginine and lysine metabolism; Belongs to the LysR transcriptional regulatory family. | 0.466 |