Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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aceFDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (E2); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (532 aa)    
Predicted Functional Partners:
lpdA
Dihydrolipoamide dehydrogenase (E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes) (glycine cleavage system L protein).
 0.998
aceE
Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.998
plu1883
Transket_pyr domain-containing protein; Unnamed protein product; Similar to 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) alpha/beta E1 chain CP0743.
 
 0.994
plu2795
Transket_pyr domain-containing protein; Unnamed protein product; Similar to 3-methyl-2-oxobutanoate dehydrogenase (lipoamide). Putative transmembrane protein.
 
 0.991
sucA
2-oxoglutarate dehydrogenase E1 component (Alpha-ketoglutarate dehydrogenase).
 0.974
sucC
succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 0.951
gltA
Citrate synthase; Belongs to the citrate synthase family.
  
 0.949
plu3138
Citrate synthase; Unnamed protein product; Weakly similar to citrate synthase.
  
 0.949
prpC
2-methylcitrate synthase (Methylcitrate synthase) (Citrate synthase 2); Belongs to the citrate synthase family.
  
 0.949
pta
Phosphate acetyltransferase (phosphotransacetylase); Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
 
 0.935
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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