Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
aldBAldehyde dehydrogenase B (Lactaldehyde dehydrogenase); Belongs to the aldehyde dehydrogenase family. (494 aa)    
Predicted Functional Partners:
plu1563
Fe-ADH domain-containing protein; Unnamed protein product; Similar to putative oxidoreductase YiaY of Escherichia coli.
 
 0.922
plu1806
Aldedh domain-containing protein; Unnamed protein product; Similar to probable aldehyde dehydrogenase.
  
  
 
0.920
goaG
4-aminobutyrate aminotransferase (gamma-amino-N-butyrate transaminase) (GABA transaminase); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.917
adhE
Aldehyde-alcohol dehydrogenase [includes: alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase [acetylating] (ACDH); pyruvate-formate-lyase deactivase (PFL deactivase)]; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
0.915
adhC
Alcohol dehydrogenase class III (glutathione-dependent formaldehyde dehydrogenase) (FDH) (FALDH); Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
  
 0.913
acs
Acetyl-coenzyme A synthetase (acetate--COA ligase) (acyl-activating enzyme); Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
   
 0.910
plu1231
CN hydrolase domain-containing protein; Unnamed protein product; Highly similar to nitrilase. Putative secreted protein.
    
  0.908
plu0142
Aldedh domain-containing protein; Unnamed protein product; Similar to NADP-dependent aldehyde dehydrogenase.
  
  
 
0.906
ackA
Acetate kinase (acetokinase); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
    
 0.905
plu2260
Unnamed protein product; Similar to beta-alanine--pyruvate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
    
 0.903
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
Server load: medium (72%) [HD]