| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ackA | acs | plu3095 | plu0074 | Acetate kinase (acetokinase); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Acetyl-coenzyme A synthetase (acetate--COA ligase) (acyl-activating enzyme); Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.927 |
| ackA | adhE | plu3095 | plu2496 | Acetate kinase (acetokinase); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Aldehyde-alcohol dehydrogenase [includes: alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase [acetylating] (ACDH); pyruvate-formate-lyase deactivase (PFL deactivase)]; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | 0.517 |
| ackA | aldB | plu3095 | plu3739 | Acetate kinase (acetokinase); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Aldehyde dehydrogenase B (Lactaldehyde dehydrogenase); Belongs to the aldehyde dehydrogenase family. | 0.914 |
| ackA | fadB | plu3095 | plu4402 | Acetate kinase (acetokinase); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Fatty oxidation complex alpha subunit [includes: enoyl-CoA hydratase; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. | 0.402 |
| ackA | fadJ | plu3095 | plu3200 | Acetate kinase (acetokinase); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Enoyl-CoA hydratase/3-hydroxybutyryl-CoA epimerase; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 0.402 |
| ackA | plu0142 | plu3095 | plu0142 | Acetate kinase (acetokinase); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Aldedh domain-containing protein; Unnamed protein product; Similar to NADP-dependent aldehyde dehydrogenase. | 0.914 |
| acs | ackA | plu0074 | plu3095 | Acetyl-coenzyme A synthetase (acetate--COA ligase) (acyl-activating enzyme); Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Acetate kinase (acetokinase); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.927 |
| acs | adhE | plu0074 | plu2496 | Acetyl-coenzyme A synthetase (acetate--COA ligase) (acyl-activating enzyme); Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Aldehyde-alcohol dehydrogenase [includes: alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase [acetylating] (ACDH); pyruvate-formate-lyase deactivase (PFL deactivase)]; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | 0.942 |
| acs | aldB | plu0074 | plu3739 | Acetyl-coenzyme A synthetase (acetate--COA ligase) (acyl-activating enzyme); Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Aldehyde dehydrogenase B (Lactaldehyde dehydrogenase); Belongs to the aldehyde dehydrogenase family. | 0.926 |
| acs | fadB | plu0074 | plu4402 | Acetyl-coenzyme A synthetase (acetate--COA ligase) (acyl-activating enzyme); Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Fatty oxidation complex alpha subunit [includes: enoyl-CoA hydratase; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. | 0.944 |
| acs | fadJ | plu0074 | plu3200 | Acetyl-coenzyme A synthetase (acetate--COA ligase) (acyl-activating enzyme); Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Enoyl-CoA hydratase/3-hydroxybutyryl-CoA epimerase; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 0.943 |
| acs | plu0142 | plu0074 | plu0142 | Acetyl-coenzyme A synthetase (acetate--COA ligase) (acyl-activating enzyme); Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Aldedh domain-containing protein; Unnamed protein product; Similar to NADP-dependent aldehyde dehydrogenase. | 0.926 |
| acs | plu1806 | plu0074 | plu1806 | Acetyl-coenzyme A synthetase (acetate--COA ligase) (acyl-activating enzyme); Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Aldedh domain-containing protein; Unnamed protein product; Similar to probable aldehyde dehydrogenase. | 0.926 |
| adhC | adhE | plu4332 | plu2496 | Alcohol dehydrogenase class III (glutathione-dependent formaldehyde dehydrogenase) (FDH) (FALDH); Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | Aldehyde-alcohol dehydrogenase [includes: alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase [acetylating] (ACDH); pyruvate-formate-lyase deactivase (PFL deactivase)]; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | 0.978 |
| adhC | aldB | plu4332 | plu3739 | Alcohol dehydrogenase class III (glutathione-dependent formaldehyde dehydrogenase) (FDH) (FALDH); Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | Aldehyde dehydrogenase B (Lactaldehyde dehydrogenase); Belongs to the aldehyde dehydrogenase family. | 0.912 |
| adhC | plu0142 | plu4332 | plu0142 | Alcohol dehydrogenase class III (glutathione-dependent formaldehyde dehydrogenase) (FDH) (FALDH); Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | Aldedh domain-containing protein; Unnamed protein product; Similar to NADP-dependent aldehyde dehydrogenase. | 0.912 |
| adhC | plu1563 | plu4332 | plu1563 | Alcohol dehydrogenase class III (glutathione-dependent formaldehyde dehydrogenase) (FDH) (FALDH); Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | Fe-ADH domain-containing protein; Unnamed protein product; Similar to putative oxidoreductase YiaY of Escherichia coli. | 0.959 |
| adhE | ackA | plu2496 | plu3095 | Aldehyde-alcohol dehydrogenase [includes: alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase [acetylating] (ACDH); pyruvate-formate-lyase deactivase (PFL deactivase)]; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Acetate kinase (acetokinase); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.517 |
| adhE | acs | plu2496 | plu0074 | Aldehyde-alcohol dehydrogenase [includes: alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase [acetylating] (ACDH); pyruvate-formate-lyase deactivase (PFL deactivase)]; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Acetyl-coenzyme A synthetase (acetate--COA ligase) (acyl-activating enzyme); Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.942 |
| adhE | adhC | plu2496 | plu4332 | Aldehyde-alcohol dehydrogenase [includes: alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase [acetylating] (ACDH); pyruvate-formate-lyase deactivase (PFL deactivase)]; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Alcohol dehydrogenase class III (glutathione-dependent formaldehyde dehydrogenase) (FDH) (FALDH); Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | 0.978 |
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