close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cyoEProtoheme IX farnesyltransferase (heme O synthase); Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (294 aa)    
Predicted Functional Partners:
cyoD
Cytochrome O ubiquinol oxidase protein cyoD (ubiquinol oxidase chain D).
 
 
 0.998
cyoB
Ubiquinol oxidase polypeptide I (cytochrome O subunit 1) (oxidase BO(3) subunit 1) (cytochrome O ubiquinol oxidase subunit 1) (ubiquinol oxidase chain A); Belongs to the heme-copper respiratory oxidase family.
 
 0.997
cyoC
Cytochrome O ubiquinol oxidase subunit III (ubiquinol oxidase chain C).
 
 
 0.997
cyoA
Ubiquinol oxidase polypeptide II precursor (cytochrome O subunit 2) (oxidase BO(3) subunit 2) (cytochrome O ubiquinol oxidase subunit 2) (ubiquinol oxidase chain B).
 
 
 0.995
hemH
Ferrochelatase (protoheme ferro-lyase) (heme synthetase); Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
   
 
 0.928
plu3880
MFS domain-containing protein; Unnamed protein product; Highly similar to probable transport protein YajR of Escherichia coli.
 
   
 0.587
nuoB
NADH dehydrogenase I chain B (NADH-ubiquinone oxidoreductase chain 2) (NUO2); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
   
  
 0.526
nuoK
NADH dehydrogenase I chain K (NADH-ubiquinone oxidoreductase chain K) (NUO11); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family.
   
  
 0.524
nuoC
NADH dehydrogenase I chain C/D (NADH-ubiquinone oxidoreductase chain 3/4) (NUO3/NUO4); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
   
  
 0.511
icd
Isocitrate dehydrogenase [NADP].
   
  
 0.504
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.