| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| bioH | plu3964 | plu0204 | plu3964 | Biotin biosynthesis protein BioH; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters. | Unnamed protein product; Similar to unknown protein YqiC of Escherichia coli. | 0.522 |
| ftsQ | hemD | plu3651 | plu4645 | Cell division protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.445 |
| ftsQ | mreD | plu3651 | plu4069 | Cell division protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | Rod shape-determining protein MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family. | 0.726 |
| ftsQ | plu1378 | plu3651 | plu1378 | Cell division protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | TPR_21 domain-containing protein; Unnamed protein product; Similar to unknown protein YfgM of Escherichia coli. | 0.546 |
| ftsQ | plu3964 | plu3651 | plu3964 | Cell division protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | Unnamed protein product; Similar to unknown protein YqiC of Escherichia coli. | 0.505 |
| ftsQ | rseB | plu3651 | plu3344 | Cell division protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | Sigma-E factor regulatory protein RseB precursor. | 0.418 |
| ftsQ | secE | plu3651 | plu0433 | Cell division protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | Preprotein translocase SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family. | 0.827 |
| hemD | ftsQ | plu4645 | plu3651 | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Cell division protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | 0.445 |
| hemD | mreD | plu4645 | plu4069 | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Rod shape-determining protein MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family. | 0.448 |
| hemD | plu1378 | plu4645 | plu1378 | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | TPR_21 domain-containing protein; Unnamed protein product; Similar to unknown protein YfgM of Escherichia coli. | 0.562 |
| hemD | plu3964 | plu4645 | plu3964 | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Unnamed protein product; Similar to unknown protein YqiC of Escherichia coli. | 0.506 |
| hemD | plu4412 | plu4645 | plu4412 | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | SCP2 domain-containing protein; Unnamed protein product; Similar to unknown protein YigP of Escherichia coli. | 0.440 |
| hemD | rseB | plu4645 | plu3344 | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Sigma-E factor regulatory protein RseB precursor. | 0.442 |
| hemD | secE | plu4645 | plu0433 | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Preprotein translocase SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family. | 0.548 |
| mreD | ftsQ | plu4069 | plu3651 | Rod shape-determining protein MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family. | Cell division protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | 0.726 |
| mreD | hemD | plu4069 | plu4645 | Rod shape-determining protein MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family. | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.448 |
| mreD | plu1378 | plu4069 | plu1378 | Rod shape-determining protein MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family. | TPR_21 domain-containing protein; Unnamed protein product; Similar to unknown protein YfgM of Escherichia coli. | 0.725 |
| mreD | plu3602 | plu4069 | plu3602 | Rod shape-determining protein MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family. | UPF0149 protein plu3602; Unnamed protein product; Similar to unknown protein YgfB of Escherichia coli; Belongs to the UPF0149 family. | 0.448 |
| mreD | plu3964 | plu4069 | plu3964 | Rod shape-determining protein MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family. | Unnamed protein product; Similar to unknown protein YqiC of Escherichia coli. | 0.562 |
| mreD | secE | plu4069 | plu0433 | Rod shape-determining protein MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family. | Preprotein translocase SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family. | 0.616 |